Self-nano-emulsifying drug-delivery systems: From the development to the current applications and challenges in oral drug delivery
Approximately one third of newly discovered drug molecules show insufficient water
solubility and therefore low oral bio-availability. Self-nano-emulsifying drug-delivery systems …
solubility and therefore low oral bio-availability. Self-nano-emulsifying drug-delivery systems …
From nanoemulsions to self-nanoemulsions, with recent advances in self-nanoemulsifying drug delivery systems (SNEDDS)
Introduction: Lipid-based drug delivery systems (LBDDS) are the most promising technique
to formulate the poorly water soluble drugs. Nanotechnology strongly influences the …
to formulate the poorly water soluble drugs. Nanotechnology strongly influences the …
Self-nano-emulsifying drug delivery systems: an update of the biopharmaceutical aspects
Introduction: Thirty percent of top marketed drugs in the USA and 70% of all new drug
candidates are lipophilic and exhibit poor water solubility. With such physicochemical …
candidates are lipophilic and exhibit poor water solubility. With such physicochemical …
[HTML][HTML] Formulation development, optimization by Box-Behnken design, characterization, in vitro, ex-vivo, and in vivo evaluation of bosentan-loaded self …
This study aimed to develop and optimize a self-nanoemulsifying drug delivery system
(SNEDDS) of bosentan (BOS) to solve its poor oral bioavailability due to low water solubility …
(SNEDDS) of bosentan (BOS) to solve its poor oral bioavailability due to low water solubility …
Self-emulsifying drug delivery systems (SEDDS): measuring energy dynamics to determine thermodynamic and kinetic stability
This research was designed to identify thermodynamically and kinetically stable lipidic self-
emulsifying formulations through simple energy dynamics in addition to highlighting and …
emulsifying formulations through simple energy dynamics in addition to highlighting and …
Enhancing Nutraceutical Bioavailability with Bilosomes: A Comprehensive Review
PNK Sarella, VT Mangam - Asian Journal of Pharmacy and …, 2024 - ajptonline.com
Nutraceuticals, encompassing vitamins, minerals, and dietary supplements, play a pivotal
role in promoting health and wellness. However, their therapeutic efficacy is often hindered …
role in promoting health and wellness. However, their therapeutic efficacy is often hindered …
Bioavailability enhanced clopidogrel-loaded solid SNEDDS: development and in-vitro/in-vivo characterization
E Abd-Elhakeem, MHM Teaima, GA Abdelbary… - Journal of Drug Delivery …, 2019 - Elsevier
The purpose of this study is to develop solid self-nanoemulsifying drug delivery systems (S-
SNEDDS) for oral bioavailability enhancement of Clopidogrel (CLP). CLP is an anti-platelet …
SNEDDS) for oral bioavailability enhancement of Clopidogrel (CLP). CLP is an anti-platelet …
Impact of solid carriers and spray drying on pre/post-compression properties, dissolution rate and bioavailability of solid self-nanoemulsifying drug delivery system …
In the present study, different solid self-nanoemulsifying drug delivery system (S-SNEDDS)
was formulated by using porous hydrophilic and hydrophobic carriers to improve the …
was formulated by using porous hydrophilic and hydrophobic carriers to improve the …
Novel nanostructured solid materials for modulating oral drug delivery from solid-state lipid-based drug delivery systems
Lipid-based drug delivery systems (LBDDS) have gained significant attention in recent
times, owing to their ability to overcome the challenges limiting the oral delivery of poorly …
times, owing to their ability to overcome the challenges limiting the oral delivery of poorly …
Formulation of solid self-nanoemulsifying drug delivery systems using N-methyl pyrrolidone as cosolvent
AG Agrawal, A Kumar, PS Gide - Drug development and industrial …, 2015 - Taylor & Francis
Atorvastatin calcium (ATRC) is a poor water soluble drug used for treatment of
hypercholesterolemia. This research is aimed to improve solubility and dissolution rate of …
hypercholesterolemia. This research is aimed to improve solubility and dissolution rate of …