The lungs are the primary target of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) infection, with severe hypoxia being the cause of death in the most critical cases …

Our understanding of, and approach to, pulmonary arterial hypertension has undergone a
paradigm shift in the past decade. Once a condition thought to be dominated by increased …

Pulmonary arterial hypertension (PAH) is a syndrome in which pulmonary arterial
obstruction increases pulmonary vascular resistance, which leads to right ventricular (RV) …

Pulmonary hypertension (PH) is a disorder that develops as a result of remodeling of the
pulmonary vasculature and is characterized by narrowing/obliteration of small pulmonary …

A 46-year-old-woman presents with exertional dyspnea and syncope and receives a
diagnosis of idiopathic pulmonary arterial hypertension. Treatment with sildenafil is …

The poorest billion people are distributed throughout the world, though most are
concentrated in rural sub-Saharan Africa and South Asia. Cardiovascular disease (CVD) …

The heart failure syndrome has been recognized as a significant contributor to
cardiovascular disease burden in sub-Saharan African for many decades. Seminal …

The incidence of congenital heart disease is approximately 8/1,000 live births and appears
to be constant around the world. The currently accepted paradigm for the development of …

Schistosomiasis is a chronic enteropathogenic disease caused by blood flukes of the genus
Schistosoma. The disease afflicts approximately 240 million individuals globally, causing …

Inflammation underlies a wide variety of physiological and pathological processes. Acute
inflammation is the initial response of the body to harmful stimuli. Chronic inflammation, by …