[HTML][HTML] How genomics can help biodiversity conservation

K Theissinger, C Fernandes, G Formenti, I Bista… - Trends in Genetics, 2023 - cell.com
The availability of public genomic resources can greatly assist biodiversity assessment,
conservation, and restoration efforts by providing evidence for scientifically informed …

[HTML][HTML] Towards population-scale long-read sequencing

W De Coster, MH Weissensteiner… - Nature Reviews …, 2021 - nature.com
Long-read sequencing technologies have now reached a level of accuracy and yield that
allows their application to variant detection at a scale of tens to thousands of samples …

The earth BioGenome project 2020: Starting the clock

HA Lewin, S Richards… - Proceedings of the …, 2022 - National Acad Sciences
November 2020 marked 2 y since the launch of the Earth BioGenome Project (EBP), which
aims to sequence all known eukaryotic species in a 10-y timeframe. Since then, significant …

Sequence locally, think globally: the Darwin Tree of Life Project

Darwin Tree of Life Project … - Proceedings of the …, 2022 - National Acad Sciences
The goals of the Earth Biogenome Project—to sequence the genomes of all eukaryotic life
on earth—are as daunting as they are ambitious. The Darwin Tree of Life Project was …

Identifying and removing haplotypic duplication in primary genome assemblies

D Guan, SA McCarthy, J Wood, K Howe, Y Wang… - …, 2020 - academic.oup.com
Motivation Rapid development in long-read sequencing and scaffolding technologies is
accelerating the production of reference-quality assemblies for large eukaryotic genomes …

Modern epigenetics methods in biological research

Y Li - Methods, 2021 - Elsevier
The definition of epigenetics refers that molecular modifications on DNA that can regulate
gene activity are independent of DNA sequence and mitotically stable. Notably, epigenetics …

[HTML][HTML] Highly contiguous assemblies of 101 drosophilid genomes

BY Kim, JR Wang, DE Miller, O Barmina, E Delaney… - Elife, 2021 - elifesciences.org
Over 100 years of studies in Drosophila melanogaster and related species in the genus
Drosophila have facilitated key discoveries in genetics, genomics, and evolution. While high …

[HTML][HTML] Advances and opportunities in malaria population genomics

DE Neafsey, AR Taylor, BL MacInnis - Nature Reviews Genetics, 2021 - nature.com
Almost 20 years have passed since the first reference genome assemblies were published
for Plasmodium falciparum, the deadliest malaria parasite, and Anopheles gambiae, the …

Why sequence all eukaryotes?

M Blaxter, JM Archibald, AK Childers… - Proceedings of the …, 2022 - National Acad Sciences
Life on Earth has evolved from initial simplicity to the astounding complexity we experience
today. Bacteria and archaea have largely excelled in metabolic diversification, but …

Latest techniques to study DNA methylation

Q Gouil, A Keniry - Essays in biochemistry, 2019 - portlandpress.com
Bisulfite sequencing is a powerful technique to detect 5-methylcytosine in DNA that has
immensely contributed to our understanding of epigenetic regulation in plants and animals …