Two of the most fascinating bacterial nanomachines—the broadly disseminated rotary
flagellum at the heart of cellular motility and the eukaryotic cell–puncturing injectisome …

The bacterial injectisome is a structurally conserved, syringe-shaped nanomachine that
spans the Gram-negative envelope and forms a continuous channel for type III secretion of …

Virulence-associated bacterial type III secretion systems are multiprotein molecular
machines that promote the pathogenicity of bacteria towards eukaryotic host cells. These …

Type-3 secretion system injectisomes are multiprotein complexes that translocate bacterial
effector proteins from the cytoplasm of gram-negative bacteria directly into the cytosol of …

Many pathogens use Type III and Type IV protein secretion systems to secrete virulence
factors from the bacterial cytosol into host cells. These systems operate through a one-step …

In the last several years, there has been a tremendous progress in the understanding of host–
pathogen interactions and the mechanisms by which bacterial pathogens modulate …

Gastrointestinale Infektionen, verursacht durch enteropathogene Escherichia coli (EPEC),
stellen nach wie vor eine gesundheitliche Bedrohung für den Menschen dar und tragen zur …

Some Gram-negative bacteria utilize type III secretion system (T3SS) as a tool in their
arsenal in the pursuit of host invasion. The T3SS works to the advantage of the pathogen …

Many pathogens use Type III and Type IV protein secretion systems to secrete virulence
factors from the bacterial cytosol into host cells. These systems operate through a one-step …

Bacteria have evolved several sophisticated assemblies to transport proteins across their
biological membranes, including those required specifically for pathogenicity. Recent …