Background: Methotrexate is an off-label therapy for atopic dermatitis. A lack of consensus
on dosing regimens poses a risk of underdosing and ineffective treatment or overdosing and …

Background Current treatment for localized scleroderma (LS) has been shown to halt
disease activity, but little is still known about patient experiences with these treatments, nor …

Background The treatment and curative effect evaluation of localized scleroderma (LS) still
perplexes many clinical workers. Purpose To investigate the efficiacy of methotrexate in the …

Objectives It was aimed to compare the characteristics of patients with pediatric and adult-
onset morphea. Methods A retrospective analysis was performed on the records of 183 adult …

Localized scleroderma with pulmonary arterial hypertension and pulmonary interstitial fibrosis
in a patient with positive Th/to antibodies: Case report and review of literature - Elinkichari …

If an authorized drug is prescribed for a use that is not described in the Summary of Product
Characteristics, this is defined as 'off-label use.'Methotrexate is often used off-label for …

Morphea, also known as localized scleroderma, is a sclerosing disease of unknown etiology
that involves mainly dermal and subcutaneous layers of skin. Several types of morphea exist …

Objective: Localized scleroderma (LS), which is also called as morphea, is a rare skin
disease with unknown etiology. LS is typically characterized by sclerosis in the dermis and …

Background Current treatment for localized scleroderma (LS) has been shown to halt
disease activity, but little is still known about patient experiences with these treatments, nor …

Aim: To evaluate juvenile localized scleroderma, which is a disease with high rates of
cosmetic and functional sequelae in children, from a pediatric rheumatology perspective …