Genetic models of human and mouse dendritic cell development and function

DA Anderson III, CA Dutertre, F Ginhoux… - Nature Reviews …, 2021 - nature.com
Dendritic cells (DCs) develop in the bone marrow from haematopoietic progenitors that have
numerous shared characteristics between mice and humans. Human counterparts of mouse …

Plasmacytoid dendritic cells: development, regulation, and function

B Reizis - Immunity, 2019 - cell.com
Plasmacytoid dendritic cells (pDCs) are a unique sentinel cell type that can detect pathogen-
derived nucleic acids and respond with rapid and massive production of type I interferon …

Dendritic cells and CD8 T cell immunity in tumor microenvironment

C Fu, A Jiang - Frontiers in immunology, 2018 - frontiersin.org
Dendritic cells (DCs) play a central role in the regulation of the balance between CD8 T cell
immunity vs. tolerance to tumor antigens. Cross-priming, a process which DCs activate CD8 …

Tolerogenic dendritic cells in autoimmunity and inflammatory diseases

O Morante-Palacios, F Fondelli, E Ballestar… - Trends in …, 2021 - cell.com
Dendritic cells (DCs), the most efficient antigen-presenting cells, are necessary for the
effective activation of naïve T cells. DCs can also acquire tolerogenic functions in vivo and in …

The multifaceted biology of plasmacytoid dendritic cells

M Swiecki, M Colonna - Nature Reviews Immunology, 2015 - nature.com
Plasmacytoid dendritic cells (pDCs) are a unique DC subset that specializes in the
production of type I interferons (IFNs). pDCs promote antiviral immune responses and have …

Dendritic cells, monocytes and macrophages: a unified nomenclature based on ontogeny

M Guilliams, F Ginhoux, C Jakubzick, SH Naik… - Nature Reviews …, 2014 - nature.com
The mononuclear phagocyte system (MPS) has historically been categorized into
monocytes, dendritic cells and macrophages on the basis of functional and phenotypical …

Distinct progenitor lineages contribute to the heterogeneity of plasmacytoid dendritic cells

PF Rodrigues, L Alberti-Servera, A Eremin… - Nature …, 2018 - nature.com
Plasmacytoid dendritic cells (pDCs) are an immune subset devoted to the production of high
amounts of type 1 interferons in response to viral infections. Whereas conventional dendritic …

[HTML][HTML] Development and function of dendritic cell subsets

A Mildner, S Jung - Immunity, 2014 - cell.com
Classical dendritic cells (cDCs) form a critical interface between innate and adaptive
immunity. As myeloid immune cell sentinels, cDCs are specialized in the sensing of …

The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting

M Merad, P Sathe, J Helft, J Miller… - Annual review of …, 2013 - annualreviews.org
Dendritic cells (DCs) form a remarkable cellular network that shapes adaptive immune
responses according to peripheral cues. After four decades of research, we now know that …

Plasmacytoid dendritic cells develop from Ly6D+ lymphoid progenitors distinct from the myeloid lineage

RJ Dress, CA Dutertre, A Giladi, A Schlitzer, I Low… - Nature …, 2019 - nature.com
Dendritic cells (DC) are currently classified as conventional DCs (cDCs) and plasmacytoid
DCs (pDCs). Through a combination of single-cell transcriptomic analysis, mass cytometry …