Tau seeding mouse models with patient brain-derived aggregates
A Robert, M Schöll, T Vogels - International Journal of Molecular Sciences, 2021 - mdpi.com
Tauopathies are a heterogeneous class of neurodegenerative diseases characterized by
intracellular inclusions of aggregated tau proteins. Tau aggregates in different tauopathies …
intracellular inclusions of aggregated tau proteins. Tau aggregates in different tauopathies …
Inhibitory roles of Apolipoprotein E Christchurch astrocytes in curbing tau propagation using human pluripotent stem cell-derived models
R Murakami, H Watanabe, H Hashimoto… - Journal of …, 2024 - Soc Neuroscience
Genetic variants in the apolipoprotein E (APOE) gene affect the onset and progression of
Alzheimer's disease (AD). The APOE Christchurch (APOE Ch) variant has been identified as …
Alzheimer's disease (AD). The APOE Christchurch (APOE Ch) variant has been identified as …
Single-domain magnetic particles with motion behavior under electromagnetic AC and DC fields are a fatal cargo in Metropolitan Mexico City pediatric and young …
L Calderón-Garcidueñas, FR Cejudo-Ruiz… - Frontiers in Human …, 2024 - frontiersin.org
Metropolitan Mexico City (MMC) children and young adults exhibit overlapping Alzheimer
and Parkinsons' diseases (AD, PD) and TAR DNA-binding protein 43 pathology with …
and Parkinsons' diseases (AD, PD) and TAR DNA-binding protein 43 pathology with …
Arc mediates intercellular tau transmission via extracellular vesicles
Intracellular neurofibrillary tangles that consist of misfolded tau protein 1 cause
neurodegeneration in Alzheimer's disease (AD) and frontotemporal dementia (FTD). Tau …
neurodegeneration in Alzheimer's disease (AD) and frontotemporal dementia (FTD). Tau …
Virus-like particle (VLP)-based vaccine targeting tau phosphorylated at Ser396/Ser404 (PHF1) site outperforms phosphorylated S199/S202 (AT8) site in reducing tau …
JP Hulse, NM Maphis, J Peabody, B Chackerian… - bioRxiv, 2024 - biorxiv.org
Tauopathies, including Alzheimers disease (AD) and Frontotemporal Dementia (FTD), are
histopathologically defined by the aggregation of hyperphosphorylated pathological tau …
histopathologically defined by the aggregation of hyperphosphorylated pathological tau …
Tau Aggregation is Altered by Mutations in its Projection Domain
K Mason-Chalmers, A Sachdeva, G Kolk, JC Touchon… - bioRxiv, 2024 - biorxiv.org
The intrinsically disordered microtubule-associated protein tau is known for its aberrant
aggregation into neurofibrillary tangles as found in neuropathologies such as Alzheimers …
aggregation into neurofibrillary tangles as found in neuropathologies such as Alzheimers …
Virus-like particle (VLP)-based vaccine targeting tau phosphorylated at Ser396/Ser404 (PHF1) site outperforms phosphorylated S199/S202 (AT8) site in reducing tau …
Tauopathies, including Alzheimer's disease (AD) and Frontotemporal Dementia (FTD), are
histopathologically defined by the aggregation of hyperphosphorylated pathological tau …
histopathologically defined by the aggregation of hyperphosphorylated pathological tau …