Blood-based biomarkers in Alzheimer disease: current state of the science and a novel collaborative paradigm for advancing from discovery to clinic

SE O'Bryant, MM Mielke, RA Rissman, S Lista… - Alzheimer's & …, 2017 - Elsevier
The last decade has seen a substantial increase in research focused on the identification of
blood-based biomarkers that have utility in Alzheimer's disease (AD). Blood-based …

Use of adjuvant bisphosphonates and other bone-modifying agents in breast cancer: a Cancer Care Ontario and American Society of Clinical Oncology clinical …

S Dhesy-Thind, GG Fletcher, PS Blanchette… - Journal of Clinical …, 2017 - ascopubs.org
Purpose To make recommendations regarding the use of bisphosphonates and other bone-
modifying agents as adjuvant therapy for patients with breast cancer. Methods Cancer Care …

Bisphosphonates and other bone agents for breast cancer

B O'Carrigan, MHF Wong, ML Willson… - Cochrane database …, 2017 - cochranelibrary.com
Background Bone is the most common site of metastatic disease associated with breast
cancer (BC). Bisphosphonates inhibit osteoclast‐mediated bone resorption, and novel …

Bone-targeted therapies in cancer-induced bone disease

S Sousa, P Clézardin - Calcified tissue international, 2018 - Springer
Cancer-induced bone disease is a major source of morbidity and mortality in cancer
patients. Thus, effective bone-targeted therapies are essential to improve disease-free …

[HTML][HTML] The anti-tumour effects of zoledronic acid

J Zekri, M Mansour, SM Karim - Journal of bone oncology, 2014 - Elsevier
Bone is the most common site for metastasis in patients with solid tumours.
Bisphosphonates are an effective treatment for preventing skeletal related events and …

[HTML][HTML] The metastatic microenvironment of breast cancer: clinical implications

RE Coleman, W Gregory, H Marshall, C Wilson, I Holen - The Breast, 2013 - Elsevier
Metastasis to bone, and indeed potentially to other sites, results from the numerous
interactions between cancer cells, haematopoietic stem cells and normal bone cells within …

Extra-skeletal effects of bisphosphonates

A Panagiotakou, M Yavropoulou, N Nasiri-Ansari… - Metabolism, 2020 - Elsevier
Abstract Background Bisphosphonates (BPs) are pyrophosphate analogues widely used in
diseases related to bone loss and increased bone turnover. Their high affinity for bone …

[HTML][HTML] Effects of neoadjuvant chemotherapy with or without zoledronic acid on pathological response: a meta-analysis of randomised trials

JR Kroep, A Charehbili, RE Coleman, RL Aft… - European Journal of …, 2016 - Elsevier
Purpose The addition of bisphosphonates to adjuvant therapy improves survival in
postmenopausal breast cancer (BC) patients. We report a meta-analysis of four randomised …

Neoadjuvant treatment of breast cancer: maximizing pathologic complete response rates to improve prognosis

S Loibl - Current Opinion in Obstetrics and Gynecology, 2015 - journals.lww.com
Neoadjuvant treatment of breast cancer: maximizing pathologi... : Current Opinion in Obstetrics
and Gynecology Neoadjuvant treatment of breast cancer: maximizing pathologic complete …

Psychological states, serum markers and survival: associations and predictors of survival in patients with renal cell carcinoma

S Prinsloo, Q Wei, SM Scott, N Tannir… - Journal of behavioral …, 2015 - Springer
This study sought to determine if there was an association between prognostic-based serum
biomarkers, survival, and psychosocial factors in patients with metastatic renal cell …