Neurophysiological mechanisms of deep brain stimulation across spatiotemporal resolutions

WJ Neumann, LA Steiner, L Milosevic - Brain, 2023 - academic.oup.com
Deep brain stimulation is a neuromodulatory treatment for managing the symptoms of
Parkinson's disease and other neurological and psychiatric disorders. Electrodes are …

Deep brain stimulation for psychiatric disorders

PE Holtzheimer, HS Mayberg - Annual review of neuroscience, 2011 - annualreviews.org
Medications, psychotherapy, and other treatments are effective for many patients with
psychiatric disorders. However, with currently available interventions, a substantial number …

Mechanisms of action of deep brain stimulation (DBS)

EB Montgomery Jr, JT Gale - Neuroscience & Biobehavioral Reviews, 2008 - Elsevier
Deep brain stimulation (DBS) is remarkably effective for a range of neurological and
psychiatric disorders that have failed pharmacological and cell transplant therapies. Clinical …

Deep brain stimulation for treatment-resistant depression: efficacy, safety and mechanisms of action

RJ Anderson, MA Frye, OA Abulseoud, KH Lee… - Neuroscience & …, 2012 - Elsevier
Deep brain stimulation (DBS), a neuromodulation therapy that has been used successfully
in the treatment of symptoms associated with movement disorders, has recently undergone …

Neuronal and synaptic adaptations underlying the benefits of deep brain stimulation for Parkinson's disease

W Xu, J Wang, XN Li, J Liang, L Song, Y Wu… - Translational …, 2023 - Springer
Deep brain stimulation (DBS) is a well-established and effective treatment for patients with
advanced Parkinson's disease (PD), yet its underlying mechanisms remain enigmatic …

Deep brain stimulation in neurological diseases and experimental models: from molecule to complex behavior

P Gubellini, P Salin, L Kerkerian-Le Goff… - Progress in …, 2009 - Elsevier
Deep brain stimulation (DBS) has proven to be capable of providing significant benefits for
several neuropathologies. It is highly effective in reducing the motor symptoms of …

Mechanisms of deep brain stimulation for obsessive compulsive disorder: effects upon cells and circuits

SK Bourne, CA Eckhardt, SA Sheth… - Frontiers in integrative …, 2012 - frontiersin.org
Deep brain stimulation (DBS) has emerged as a safe, effective, and reversible treatment for
a number of movement disorders. This has prompted investigation of its use for other …

High frequency stimulation can block axonal conduction

AL Jensen, DM Durand - Experimental neurology, 2009 - Elsevier
High frequency stimulation (HFS) is used to control abnormal neuronal activity associated
with movement, seizure, and psychiatric disorders. Yet, the mechanisms of its therapeutic …

Deep brain stimulation for obsessive–compulsive disorder: a systematic review and meta-analysis

S Kisely, K Hall, D Siskind, J Frater, S Olson… - Psychological …, 2014 - cambridge.org
Background. Deep brain stimulation (DBS) is increasingly being applied to psychiatric
conditions such as obsessive–compulsive disorder (OCD), major depression and anorexia …

Axonal and synaptic failure suppress the transfer of firing rate oscillations, synchrony and information during high frequency deep brain stimulation

R Rosenbaum, A Zimnik, F Zheng, RS Turner… - Neurobiology of …, 2014 - Elsevier
High frequency deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a widely
used treatment for Parkinson's disease, but its effects on neural activity in basal ganglia …