ASGR1 Deficiency Inhibits Atherosclerosis in Western Diet–Fed ApoE−/− Mice by Regulating Lipoprotein Metabolism and Promoting Cholesterol Efflux
Y Zhang, X Jiang, W Wang, L Lei, R Sheng… - … and Vascular Biology, 2024 - ahajournals.org
BACKGROUND: Atherosclerosis is the most common cause of cardiovascular diseases.
Clinical studies indicate that loss-of-function ASGR1 (asialoglycoprotein receptor 1) is …
Clinical studies indicate that loss-of-function ASGR1 (asialoglycoprotein receptor 1) is …
[HTML][HTML] Beyond conventional treatment: ASGR1 Leading the new era of hypercholesterolemia management
J Song, Y Fang, X Rao, L Wu, C Zhang, J Ying… - Biomedicine & …, 2024 - Elsevier
Cardiovascular disease (CVD) remains a leading cause of mortality worldwide, with
hypercholesterolemia being a major risk factor. Although various lipid-lowering therapies …
hypercholesterolemia being a major risk factor. Although various lipid-lowering therapies …
ASGR1 deficiency improves atherosclerosis but alters liver metabolism in ApoE-/- mice
Abstract The asialoglycoprotein receptor 1 (ASGR1), a multivalent carbohydrate-binding
receptor that primarily is responsible for recognizing and eliminating circulating …
receptor that primarily is responsible for recognizing and eliminating circulating …
Adding a New Piece to the ASGR1 Puzzle: ANGPTL3
I Garcia-Arcos - Arteriosclerosis, Thrombosis, and Vascular …, 2024 - ahajournals.org
ASGR1 (asialoglycoprotein receptor subunit 1). Individuals carrying these variants showed
decreased levels of plasma non-HDL (high-density lipoprotein)-cholesterol and a lower risk …
decreased levels of plasma non-HDL (high-density lipoprotein)-cholesterol and a lower risk …
Cross-sectional, interventional, and causal investigation of insulin sensitivity using plasma proteomics in diverse populations
Background: We previously reported significant correlations between a direct measure of
insulin sensitivity (IS) and blood levels of proteins measured using the Proximity Extension …
insulin sensitivity (IS) and blood levels of proteins measured using the Proximity Extension …