Background The use of low-value care (LVC) is a persistent problem that calls for
knowledge about strategies for de-implementation. However, studies are dispersed across …

Background: Inappropriate health care leads to negative patient experiences, poor health
outcomes and inefficient use of resources. We aimed to conduct a systematic review of …

Importance Incidental findings on screening and diagnostic tests are common and may
prompt cascades of testing and treatment that are of uncertain value. No study to date has …

Background: The ECG remains the most widely used diagnostic test for characterization of
cardiac structure and electrical activity. We hypothesized that parallel advances in …

Importance Cardiovascular disease (CVD), which encompasses atherosclerotic conditions
such as coronary heart disease, cerebrovascular disease, and peripheral arterial disease, is …

Importance Low-value care is prevalent in the United States, yet little is known about the
downstream health care use triggered by low-value services. Measurement of such care …

Importance Studies of low-value care have focused on the prevalence of low-value care
interventions but have rarely quantified downstream consequences of these interventions for …

Background A considerable proportion of interventions provided to patients lack evidence of
their effectiveness. This implies that patients may receive ineffective, unnecessary or even …

Importance The resting electrocardiogram (ECG) is commonly performed for cardiovascular
disease (CVD) screening purposes in Japan. However, evidence is limited regarding the …

Objective To understand the consequences of functional cardiac stress testing among
patients considering noncardiac nonophthalmologic surgery. Design A retrospective cohort …