The need for innovative anticancer treatments with high effectiveness and low toxicity is
urgent due to the development of malignancies that are resistant to chemotherapeutic …

There is no doubt that significant progress has been made in tumor therapy in the past
decades. However, the discovery of new molecules with potential antitumor properties still …

A novel series of six [1, 2, 4] triazolo [3, 4-a] isoquinolin-3-yl)-3-(1, 3-diphenyl-1 H-pyrazol-4-
yl) prop-2-en-1-ones (3a–3f) was designed and synthesized. They were characterized …

Several studies have indicated the potential therapeutic outcomes of combining selective
COX-2 inhibitors with tubulin-targeting anticancer agents. In the current study, a novel series …

Background Ehrlich solid carcinoma (ESC) is characterized by rapid proliferation and a short
survival time. Because Ehrlich ascites carcinoma (EAC) resembles human cancer cells …

Background Triple-negative breast cancer (TNBC) is a lethal mammary carcinoma subtype
that affects females and is associated with a worse prognosis. Chemotherapy is the only …

Background Cancer is the second-leading cause of death worldwide. According to a 2018
WHO report, 9.6 million deaths occurred globally due to cancer. Ehrlich carcinoma is …

Ovarian cancer ranks among the most severe forms of cancer affecting the female
reproductive organs, posing a significant clinical challenge primarily due to the development …

A novel series of 2‐cyano‐N‐(tetrahydrobenzo [b] thiophen‐2‐yl) acrylamide derivatives
were synthesized and their structures were confirmed using several spectral tools. All …

Fungal deterioration is one of the major factors that significantly contribute to mummy
cartonnage damage. Isolation and molecular identification of thirteen fungal species …