A comprehensive review on different approaches for tumor targeting using nanocarriers and recent developments with special focus on multifunctional approaches

BP Sahu, R Baishya, JL Hatiboruah, D Laloo… - Journal of …, 2022 - Springer
Background Despite tremendous advancements in cancer treatment delivery, we are still far
from achieving successful cancer prognosis and cure. The use of new nanocarriers for site …

Anticancer potential of phytochemicals derived from mangrove plants: Comprehensive mechanistic insights

R Chowdhury, MS Bhuia, MS Al Hasan… - Food Science & …, 2024 - Wiley Online Library
Cancer is a collection of illnesses characterized by aberrant cellular proliferation that can
infiltrate or metastasize to distant anatomical sites, posing a notable threat to human well …

Comparative Assessment of the Antioxidant and Anticancer Activities of Plicosepalus acacia and Plicosepalus curviflorus: Metabolomic Profiling and In Silico Studies

EE Eltamany, MS Goda, MS Nafie, AM Abu-Elsaoud… - Antioxidants, 2022 - mdpi.com
This study presents a comparison between two mistletoe plants—P. acacia and P.
curviflorus—regarding their total phenolic contents and antioxidant and anticancer activities …

Zein nanoparticles as nontoxic delivery system for maytansine in the treatment of non-small cell lung cancer

X Yu, H Wu, H Hu, Z Dong, Y Dang, Q Qi, Y Wang… - Drug …, 2020 - Taylor & Francis
Purpose Maytansine (DM1) is a potent anticancer drug and limited in clinical application due
to its poor water solubility and toxic side effects. Zein is widely used in nano drug delivery …

miR‐215‐5p is an anticancer gene in multiple myeloma by targeting RUNX1 and deactivating the PI3K/AKT/mTOR pathway

S Liu, Y Zhang, C Huang, S Lin - Journal of cellular …, 2020 - Wiley Online Library
This study examined the underlying mechanism of miR‐215‐5p in multiple myeloma (MM) at
the molecular level. miR‐215‐5p was upregulated in bone marrow specimens of patients …

MAGE-A1 in lung adenocarcinoma as a promising target of chimeric antigen receptor T cells

Y Mao, W Fan, H Hu, L Zhang, J Michel, Y Wu… - Journal of hematology & …, 2019 - Springer
Abstract Background Cancer/testis antigens (CTAs) are a special type of tumor antigen and
are believed to act as potential targets for cancer immunotherapy. Methods In this study, we …

A New Saponin (Zygo-albuside D) from Zygophyllum album Roots Triggers Apoptosis in Non-Small Cell Lung Carcinoma (A549 Cells) through CDK-2 Inhibition

EE Eltamany, MS Nafie, DM Hal, MS Abdel-Kader… - ACS …, 2023 - ACS Publications
Phytochemical study of the ethyl acetate root extract of Zygophyllum album has resulted in
the isolation of a new saponin, Zygo-albuside D (1), along with two known compounds;(3-O …

Natural and biomimetic antitumor pyrazoles, a perspective

NE Santos, ARF Carreira, VLM Silva, SS Braga - Molecules, 2020 - mdpi.com
The present review presents an overview of antitumor pyrazoles of natural or bioinspired
origins. Pyrazole compounds are relatively rare in nature, the first ones having been …

Unveiling the cutting-edge synthetic methods and multifaceted applications of bis (pyrazolyl) methanes: A comprehensive review of recent advances

P Teli, N Sahiba, S Agarwal - Synthetic Communications, 2023 - Taylor & Francis
Bis (pyrazolyl) methanes are basically the dimer of pyrazoles, attached with various linkers
such as aliphatic, aromatic or heterocyclic moieties. This scaffold has been studied for its …

Novel pyridinecarboxaldehyde thiosemicarbazone conjugated magnetite nanoparticulates (MNPs) promote apoptosis in human lung cancer A549 cells

A Habibi, SA Sadat Shandiz, A Salehzadeh… - JBIC Journal of …, 2020 - Springer
The present study highlights the apoptotic activity of magnetic Fe 3 O 4 nanoparticulates
functionalized by glutamic acid and 2-pyridinecarboxaldehyde thiosemicarbazone (PTSC) …