Cerebral ischemic stroke is characterized by acute ischemia in a certain part of the brain,
which leads to brain cells necrosis, apoptosis, ferroptosis, pyroptosis, etc. At present, there …

The thyroid gland has a special relationship with oxidative stress. On the one hand, like all
other tissues, it must defend itself against reactive oxygen species (ROS). On the other hand …

Purpose Iodine is an essential micronutrient required for thyroid hormone biosynthesis.
However, overtreatment with iodine can unfavorably affect thyroid physiology. The aim of …

Spinal cord injury (SCI) is a serious, disabling injury to the central nervous system that can
lead to motor, sensory, and autonomic dysfunction below the injury plane. SCI can be …

The Keap1/Nrf2 pathway is a key mediator of general redox and tissue-specific
homeostasis. It also exerts a dual role in cancer, by preventing cell transformation of normal …

The aim of the present study was to investigate the potential mechanism underlying the anti‑
obesity‑asthmatic effects of resveratrol (RSV) in a rat model of obese‑asthma. Rat models of …

Background: The thyroid gland has a special relationship with oxidative stress. While
generation of oxidative substances is part of normal iodide metabolism during thyroid …

Background: Several single-nucleotide polymorphisms (SNPs) are known to increase the
risk of Hashimoto's thyroiditis (HT); such SNPs reside in thyroid-specific genes or in genes …

Background: Thyroid follicular cells have physiologically high levels of reactive oxygen
species because oxidation of iodide is essential for the iodination of thyroglobulin (Tg) …

Background. The KEAP1/NRF2 pathway has been widely investigated in tumors since it was
implicated in cancer cells survival and therapies resistance. In lung tumors the deregulation …