Development of anticancer agents from plant-derived sesquiterpene lactones

Y Ren, J Yu, A Douglas Kinghorn - Current medicinal chemistry, 2016 - ingentaconnect.com
Sesquiterpene lactones are of considerable interest due to their potent bioactivities,
including cancer cell cytotoxicity and antineoplastic efficacy in in vivo studies. Among these …

Antiparasitic activity of chicory (Cichorium intybus) and its natural bioactive compounds in livestock: a review

M Peña-Espinoza, AH Valente, SM Thamsborg… - Parasites & …, 2018 - Springer
Increasing drug resistance in gastrointestinal (GI) parasites of livestock and concerns about
chemical residues in animal products and the environment are driving the development of …

Bitter is better: wild greens used in the blue zone of Ikaria, Greece

A Pieroni, G Morini, M Piochi, N Sulaiman, R Kalle… - Nutrients, 2023 - mdpi.com
The current study reports an ethnobotanical field investigation of traditionally gathered and
consumed wild greens (Chorta) in one of the five so-called Blue Zones in the world: Ikaria …

Secondary metabolites of seagrasses (Alismatales and Potamogetonales; Alismatidae): Chemical diversity, bioactivity, and ecological function

C Zidorn - Phytochemistry, 2016 - Elsevier
Seagrasses are the only higher plants living in fully marine environments; they play a
significant role in coastal ecosystems. Seagrasses inhabit the coastal shelves of all …

Can phylogeny predict chemical diversity and potential medicinal activity of plants? A case study of Amaryllidaceae

N Rønsted, MRE Symonds, T Birkholm… - BMC evolutionary …, 2012 - Springer
Background During evolution, plants and other organisms have developed a diversity of
chemical defences, leading to the evolution of various groups of specialized metabolites …

Reversed-phase ultra-high-performance liquid chromatography coupled to electrospray ionization-quadrupole-time-of-flight mass spectrometry as a powerful tool for …

IM Abu-Reidah, MM Contreras, D Arráez-Román… - … of Chromatography A, 2013 - Elsevier
Lettuce (Lactuca sativa), a leafy vegetal widely consumed worldwide, fresh cut or minimally
processed, constitutes a major dietary source of natural antioxidants and bioactive …

Sesquiterpene lactones: More than protective plant compounds with high toxicity

GF Padilla-Gonzalez, FA dos Santos… - Critical Reviews in …, 2016 - Taylor & Francis
Sesquiterpene lactones (STLs) constitute a large group of secondary metabolites that are
widely distributed in several angiosperm plant families and a few bryophytes, including …

Biochemical conservation and evolution of germacrene A oxidase in Asteraceae

DT Nguyen, JC Göpfert, N Ikezawa, G MacNevin… - Journal of Biological …, 2010 - ASBMB
Sesquiterpene lactones are characteristic natural products in Asteraceae, which
constitutes∼ 8% of all plant species. Despite their physiological and pharmaceutical …

The genus Scorzonera L.(Asteraceae): a comprehensive review on traditional uses, phytochemistry, pharmacology, toxicology, chemotaxonomy, and other …

Y Gong, ZN Shi, J Yu, XF He, XH Meng, QX Wu… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance The genus Scorzonera L. comprises of
approximately 175 species, which are mainly distributed in temperate and arid regions of …

Sesquiterpene lactones and their precursors as chemosystematic markers in the tribe Cichorieae of the Asteraceae revisited: An update (2008–2017)

O Shulha, C Zidorn - Phytochemistry, 2019 - Elsevier
Ten years after the first overview on sesquiterpene lactones in the Cichorieae tribe of the
Asteraceae family, we present an update. This review summarizes all chemosystematically …