Liver cancer is the second most frequent cause of cancer-related death globally. The main
histological subtype is hepatocellular carcinoma (HCC), which is derived from hepatocytes …

Abstract Interleukin 22 (IL-22), a member of the IL-10 cytokine family and is an emerging
CD4+ Th cytokine that plays an important role in anti-microbial defense, homeostasis and …

The recent outbreak of coronavirus disease-19 (COVID-19) continues to drastically affect
healthcare throughout the world. To date, no approved treatment regimen or vaccine is …

Hepatitis C is an inflammatory liver disease caused by the single-stranded RNA (ssRNA)
hepatitis C virus (HCV). The genetic diversity of the virus and quasispecies produced during …

During recent decades, a great variety of viral and host targets have been exploited for the
discovery of antiviral agents against human infectious diseases. 1 Although significant …

The COVID-19 pandemic has negatively affected human life globally. It has led to economic
crises and health emergencies across the world, spreading rapidly among the human …

Hepatitis C Virus (HCV), affecting millions of people worldwide, is the leading cause of liver
disorder, cirrhosis, and hepatocellular carcinoma. HCV is genetically diverse having eight …

Hepatitis is an inflammatory liver disease primarily caused by hepatitis A (HAV), B (HBV), C
(HCV), D (HDV), and E (HEV) viruses. The chronic forms of hepatitis resulting from HBV and …

Microvirin (MVN) is one of the human immunodeficiency virus (HIV-1) entry inhibitor lectins,
which consists of two structural domains sharing 35% sequence identity and contrary to …

Virtual screening of large chemical libraries is essential to support computer-aided drug
development, providing a rapid and low-cost approach for further experimental validation …