Materials design by synthetic biology

TC Tang, B An, Y Huang, S Vasikaran, Y Wang… - Nature Reviews …, 2021 - nature.com
Synthetic biology applies genetic tools to engineer living cells and organisms analogous to
the programming of machines. In materials synthetic biology, engineering principles from …

Machine learning for metabolic engineering: A review

CE Lawson, JM Martí, T Radivojevic… - Metabolic …, 2021 - Elsevier
Abstract Machine learning provides researchers a unique opportunity to make metabolic
engineering more predictable. In this review, we offer an introduction to this discipline in …

Biosensors and their applications–A review

P Mehrotra - Journal of oral biology and craniofacial research, 2016 - Elsevier
The various types of biosensors such as enzyme-based, tissue-based, immunosensors,
DNA biosensors, thermal and piezoelectric biosensors have been deliberated here to …

[HTML][HTML] Pseudomonas putida as a functional chassis for industrial biocatalysis: from native biochemistry to trans-metabolism

PI Nikel, V de Lorenzo - Metabolic engineering, 2018 - Elsevier
The itinerary followed by Pseudomonas putida from being a soil-dweller and plant colonizer
bacterium to become a flexible and engineer-able platform for metabolic engineering stems …

Optogenetic regulation of engineered cellular metabolism for microbial chemical production

EM Zhao, Y Zhang, J Mehl, H Park, MA Lalwani… - Nature, 2018 - nature.com
The optimization of engineered metabolic pathways requires careful control over the levels
and timing of metabolic enzyme expression,,,. Optogenetic tools are ideal for achieving such …

Metabolic burden: cornerstones in synthetic biology and metabolic engineering applications

G Wu, Q Yan, JA Jones, YJ Tang, SS Fong… - Trends in …, 2016 - cell.com
Engineering cell metabolism for bioproduction not only consumes building blocks and
energy molecules (eg, ATP) but also triggers energetic inefficiency inside the cell. The …

Semi-synthetic artemisinin: a model for the use of synthetic biology in pharmaceutical development

CJ Paddon, JD Keasling - Nature reviews microbiology, 2014 - nature.com
Recent developments in synthetic biology, combined with continued progress in systems
biology and metabolic engineering, have enabled the engineering of microorganisms to …

Nanomaterials for healthcare biosensing applications

M Pirzada, Z Altintas - Sensors, 2019 - mdpi.com
In recent years, an increasing number of nanomaterials have been explored for their
applications in biomedical diagnostics, making their applications in healthcare biosensing a …

[HTML][HTML] Engineered biomembrane-derived nanoparticles for nanoscale theranostics

Z Wu, H Zhang, J Yan, Y Wei, J Su - Theranostics, 2023 - ncbi.nlm.nih.gov
Currently, biological membrane-derived nanoparticles (NPs) have shown enormous
potential as drug delivery vehicles due to their outstanding biomimetic properties. To make …

Computational protein design enables a novel one-carbon assimilation pathway

JB Siegel, AL Smith, S Poust… - Proceedings of the …, 2015 - National Acad Sciences
We describe a computationally designed enzyme, formolase (FLS), which catalyzes the
carboligation of three one-carbon formaldehyde molecules into one three-carbon …