Lactate metabolism in human health and disease

X Li, Y Yang, B Zhang, X Lin, X Fu, Y An… - Signal transduction and …, 2022 - nature.com
The current understanding of lactate extends from its origins as a byproduct of glycolysis to
its role in tumor metabolism, as identified by studies on the Warburg effect. The lactate …

Design of therapeutic biomaterials to control inflammation

Z Tu, Y Zhong, H Hu, D Shao, R Haag… - Nature Reviews …, 2022 - nature.com
Inflammation plays an important role in the response to danger signals arising from damage
to our body and in restoring homeostasis. Dysregulated inflammatory responses occur in …

[HTML][HTML] The compelling link between physical activity and the body's defense system

DC Nieman, LM Wentz - Journal of sport and health science, 2019 - Elsevier
This review summarizes research discoveries within 4 areas of exercise immunology that
have received the most attention from investigators:(1) acute and chronic effects of exercise …

Prostaglandin E2 and cancer: insight into tumor progression and immunity

F Finetti, C Travelli, J Ercoli, G Colombo, E Buoso… - Biology, 2020 - mdpi.com
Simple Summary Inflammation is assessed as a hallmark of cancer and it is now widely
recognized that there exists a direct causal link between inflammation and tumors. Among …

Calprotectin (S100A8/S100A9): a key protein between inflammation and cancer

F Shabani, A Farasat, M Mahdavi, N Gheibi - Inflammation Research, 2018 - Springer
Abstract Background Calprotectin (S100A8/S100A9), a heterodimeric EF-hand Ca 2+
binding protein, are abundant in cytosol of neutrophils and are involved in inflammatory …

Transition metal‐based therapies for inflammatory diseases

Y Song, Q You, X Chen - Advanced Materials, 2023 - Wiley Online Library
Inflammatory disease (ID) is a general term that covers all diseases in which chronic
inflammation performs as the major manifestation of pathogenesis. Traditional therapies …

Structural transformative antioxidants for dual‐responsive anti‐inflammatory delivery and photoacoustic inflammation imaging

C Zhao, J Chen, J Ye, Z Li, L Su, J Wang… - Angewandte …, 2021 - Wiley Online Library
We have synthesized a PEGylated, phenylboronic acid modified L‐DOPA pro‐antioxidant
(pPAD) that can self‐assemble into nanoparticles (pPADN) for the loading of a model …

Potential effects of geraniol on cancer and inflammation-related diseases: A review of the recent research findings

R Ben Ammar - Molecules, 2023 - mdpi.com
Geraniol (GNL), a natural monoterpene, is found in many essential oils of fruits, vegetables,
and herbs, including lavender, citronella, lemongrass, and other medicinal and aromatic …

The shaping of a B cell pool maximally responsive to infections

N Baumgarth - Annual review of immunology, 2021 - annualreviews.org
B cell subsets differ in development, tissue distribution, and mechanisms of activation. In
response to infections, however, all can differentiate into extrafollicular plasmablasts that …

Polydatin: pharmacological mechanisms, therapeutic targets, biological activities, and health benefits

A Karami, S Fakhri, L Kooshki, H Khan - Molecules, 2022 - mdpi.com
Polydatin is a natural potent stilbenoid polyphenol and a resveratrol derivative with
improved bioavailability. Polydatin possesses potential biological activities predominantly …