Enzymes fold into unique three-dimensional structures to distribute their reactive amino acid
residues, but environmental changes can disrupt their essential folding and lead to …

Background: The active site of [NiFe] hydrogenase, a heterodimeric protein, is suggested to
be a binuclear Ni–Fe complex having three diatomic ligands to the Fe atom and three …

Guanidines are highly useful ligands which have conquered coordination chemistry within
the last 20 years. Their CN 3 moiety allows multiple substitution patterns which enables …

Introduction: Compounds containing guanidine moiety, originating both from natural and
synthetic sources, have found potential applications in both synthetic and medicinal …

Functional groups in natural organic matter have the potential to interact with and stabilize
iron (Fe) redox species (ferric, ferrous) through complexation reactions. In this study, iron …

The chemical synthesis of the 184‐residue ferric heme‐binding protein nitrophorin 4 was
accomplished by sequential couplings of five unprotected peptide segments using α …

Nitrophorins represent a unique class of heme proteins that are able to perform the delicate
transportation and release of the free-radical gaseous messenger nitric oxide (NO) in a pH …

The combination of X-ray diffraction experiments with optical methods such as Raman,
UV/Vis absorption and fluorescence spectroscopy greatly enhances and complements the …

Combining macromolecular crystallography with in crystallo micro-spectrophotometry yields
valuable complementary information on the sample, including the redox states of metal …

Nitrophorins (NPs) catalyze the nitrite dismutation reaction that is unprecedented in
ferriheme proteins. Despite progress in studying the reaction mechanism, fundamental …