Interactions between bacteriophage proteins and bacterial proteins are important for efficient
infection of the host cell. The phage proteins involved in these bacteriophage–host …

Control of transcription is crucial for correct gene expression and orderly development. For
many years, bacteriophage T4 has provided a simple model system to investigate …

Phage diversity significantly contributes to ecology and evolution of new bacterial species
through horizontal gene transfer. Therefore, it is essential to understand the mechanisms …

Bordetella pertussis causes whooping cough, an infectious disease that is reemerging
despite widespread vaccination. A more complete understanding of B. pertussis pathogenic …

Bacteriophage T4 middle promoters are activated through a process called σ appropriation,
which requires the concerted effort of two T4-encoded transcription factors: AsiA and MotA …

Abstract Nucleoid Associated Proteins (NAPs) organize the bacterial chromosome within the
nucleoid. The interaction of the NAP H-NS with DNA also represses specific host and …

The licensed oral, live-attenuated bacterial vaccine for typhoid fever, Salmonella enterica
serovar Typhi strain Ty21a, has also been utilized as a vaccine delivery platform for …

The primary sigma factor of Staphylococcus aureus, σSA, regulates the transcription of many
genes, including several essential genes, in this bacterium via specific recognition of …

Bordetella pertussis BvgA is a global response regulator that activates virulence genes,
including adhesin-encoding fim3 and fhaB. At the fhaB promoter, P fhaB, a BvgA binding site …

The lytic bacteriophage T4 employs multiple phage-encoded early proteins to takeover the
Escherichia coli host. However, the functions of many of these proteins are not known. In this …