[HTML][HTML] Metalated covalent organic frameworks: from synthetic strategies to diverse applications

Q Guan, LL Zhou, YB Dong - Chemical Society Reviews, 2022 - pubs.rsc.org
Covalent organic frameworks (COFs) are a class of organic crystalline porous materials
discovered in the early 21st century that have become an attractive class of emerging …

Construction of covalent organic frameworks via multicomponent reactions

Q Guan, LL Zhou, YB Dong - Journal of the American Chemical …, 2023 - ACS Publications
Multicomponent reactions (MCRs) combine at least three reactants to afford the desired
product in a highly atom-economic way and are therefore viewed as efficient one-pot …

Natural sunlight photocatalytic synthesis of benzoxazole-bridged covalent organic framework for photocatalysis

CJ Wu, XY Li, TR Li, MZ Shao, LJ Niu… - Journal of the …, 2022 - ACS Publications
Although natural sunlight-mediated photocatalysis is a clean, efficient, and green approach
to access organic products, its application in the synthesis of covalent organic frameworks …

Construction of covalent organic frameworks via a visible-light-activated photocatalytic multicomponent reaction

GB Wang, YJ Wang, JL Kan, KH Xie… - Journal of the …, 2023 - ACS Publications
Multicomponent reactions (MCRs), as a powerful one-pot combinatorial synthesis tool, have
been recently applied to the synthesis of covalent organic frameworks (COFs). Compared …

[HTML][HTML] A biodegradable covalent organic framework for synergistic tumor therapy

WY Li, JJ Wan, JL Kan, B Wang, T Song, Q Guan… - Chemical …, 2023 - pubs.rsc.org
Stimulus-responsive biodegradable nanocarriers with tumor-selective targeted drug delivery
are critical for cancer therapy. Herein, we report for the first time a redox-responsive disulfide …

A vinyl-decorated covalent organic framework for ferroptotic cancer therapy via visible-light-triggered cysteine depletion

Q Guan, LL Zhou, W Zhou, YB Dong - Journal of Materials Chemistry B, 2022 - pubs.rsc.org
Biothiols, including glutathione (GSH) and cysteine, are important reductants that maintain
intracellular redox homeostasis. Recent studies have demonstrated that cysteine deprivation …

[HTML][HTML] Ambient synthesis of an iminium-linked covalent organic framework for synergetic RNA interference and metabolic therapy of fibrosarcoma

LL Zhou, Q Guan, W Zhou, JL Kan, YB Dong - Chemical Science, 2022 - pubs.rsc.org
Small interfering RNA (siRNA)-mediated gene silencing is a promising therapeutic
approach. Herein, we report the ambient synthesis of a positively charged iminium-linked …

Covalent Organic Frameworks: Opportunities for Rational Materials Design in Cancer Therapy

LL Zhou, Q Guan, YB Dong - … Chemie International Edition, 2024 - Wiley Online Library
Nanomedicines are extensively used in cancer therapy. Covalent organic frameworks
(COFs) are crystalline organic porous materials with several benefits for cancer therapy …

[HTML][HTML] An iodide-containing covalent organic framework for enhanced radiotherapy

LL Zhou, Q Guan, W Zhou, JL Kan, YB Dong - Chemical Science, 2023 - pubs.rsc.org
Metal-free radiosensitizers, particularly iodine, have shown promise in enhancing
radiotherapy due to their suitable X-ray absorption capacities and negligible biotoxicities …

Strategies for utilizing covalent organic frameworks as host materials for the integration and delivery of bioactives

L He, L Wang, Z He, CH Pang, B Tang, A Wu, J Li - Materials Horizons, 2024 - pubs.rsc.org
Covalent organic frameworks (COFs), a new and developing class of porous framework
materials, are considered a type of promising carrier for the integration and delivery of …