Microbiota succession throughout life from the cradle to the grave

C Martino, AH Dilmore, ZM Burcham… - Nature Reviews …, 2022 - nature.com
Associations between age and the human microbiota are robust and reproducible. The
microbial composition at several body sites can predict human chronological age relatively …

Intestinal 'infant-type'bifidobacteria mediate immune system development in the first 1000 days of life

C Lin, Y Lin, H Zhang, G Wang, J Zhao, H Zhang… - Nutrients, 2022 - mdpi.com
Immune system maturation begins early in life, but few studies have examined how early-life
gut microbiota colonization educates the neonatal immune system. Bifidobacteria …

[HTML][HTML] Bifidobacteria-mediated immune system imprinting early in life

BM Henrick, L Rodriguez, T Lakshmikanth, C Pou… - Cell, 2021 - cell.com
Immune-microbe interactions early in life influence the risk of allergies, asthma, and other
inflammatory diseases. Breastfeeding guides healthier immune-microbe relationships by …

[HTML][HTML] A distinct clade of Bifidobacterium longum in the gut of Bangladeshi children thrives during weaning

T Vatanen, QY Ang, L Siegwald, SA Sarker, CI Le Roy… - Cell, 2022 - cell.com
The gut microbiome has an important role in infant health and development. We
characterized the fecal microbiome and metabolome of 222 young children in Dhaka …

Human milk oligosaccharides modify the strength of priority effects in the Bifidobacterium community assembly during infancy

MF Laursen, HM Roager - The ISME Journal, 2023 - academic.oup.com
Despite the significant role of the gut microbiota in infant health and development, little is
known about the ecological processes determining gut microbial community assembly …

Breastfeeding enrichment of B. longum subsp. infantis mitigates the effect of antibiotics on the microbiota and childhood asthma risk

DLY Dai, C Petersen, C Hoskinson, KL Del Bel… - Med, 2023 - cell.com
Background Early antibiotic exposure is linked to persistent disruption of the infant gut
microbiome and subsequent elevated pediatric asthma risk. Breastfeeding acts as a primary …

Gut microbiome and breast-feeding: Implications for early immune development

EC Davis, VP Castagna, DA Sela, MA Hillard… - Journal of Allergy and …, 2022 - Elsevier
Establishment of the gut microbiome during early life is a complex process with lasting
implications for an individual's health. Several factors influence microbial assembly; …

[PDF][PDF] Human milk antibodies to global pathogens reveal geographic and interindividual variations in IgA and IgG

JJ Campo, AE Seppo, AZ Randall, J Pablo… - Journal of Clinical …, 2024 - jci.org
BACKGROUND The use of high-throughput technologies has enabled rapid advancement
in the knowledge of host immune responses to pathogens. Our objective was to compare the …

Longitudinal quantification of Bifidobacterium longum subsp. infantis reveals late colonization in the infant gut independent of maternal milk HMO composition

D Ennis, S Shmorak, E Jantscher-Krenn… - Nature …, 2024 - nature.com
Breast milk contains human milk oligosaccharides (HMOs) that cannot be digested by
infants, yet nourish their developing gut microbiome. While Bifidobacterium are the best …

[HTML][HTML] Evidence for human milk as a biological system and recommendations for study design—a report from “Breastmilk Ecology: Genesis of Infant Nutrition (BEGIN …

SM Donovan, N Aghaeepour, A Andres… - The American Journal of …, 2023 - Elsevier
Human milk contains all of the essential nutrients required by the infant within a complex
matrix that enhances the bioavailability of many of those nutrients. In addition, human milk is …