Background Tuberculosis (TB) is the world's leading infectious cause of death.
Extrapulmonary TB accounts for 15% of TB cases, but the proportion is increasing, and over …

Background Every year, an estimated one million children and young adolescents become
ill with tuberculosis, and around 226,000 of those children die. Xpert MTB/RIF Ultra (Xpert …

Epidemiologists are often confronted with datasets to analyse which contain measurement
error due to, for instance, mistaken data entries, inaccurate recordings and measurement …

Background Xpert MTB/RIF Ultra (Xpert Ultra) and Xpert MTB/RIF are World Health
Organization (WHO)‐recommended rapid nucleic acid amplification tests (NAATs) widely …

Background Every year, at least one million children become ill with tuberculosis and
around 200,000 children die. Xpert MTB/RIF and Xpert Ultra are World Health Organization …

Tuberculosis (TB) in humans is caused by Mycobacterium tuberculosis (Mtb). It is estimated
that 70 million children (< 15 years) are currently infected with Mtb, with 1.2 million each year …

Rationale: Microbiological confirmation of pulmonary tuberculosis in children is desirable.
Objectives: To investigate the diagnostic accuracy and incremental yield of Xpert MTB/RIF …

Chagas disease affects an estimated 300,000 individuals in the United States. Diagnosis in
the chronic phase requires positive results from two different IgG serological tests. Three …

Abstract The World Health Organization's (WHO)“End TB” strategy calls for development and
implementation of novel tuberculosis (TB) diagnostics. Sputum-based diagnostics are …

Tuberculosis (TB) remains a significant, yet under-recognized cause of death in the pediatric
population, with a WHO estimate of 1 million new cases of childhood TB in 2016 resulting in …