COVID-19, cytokines, inflammation, and spices: How are they related?

AB Kunnumakkara, V Rana, D Parama, K Banik… - Life sciences, 2021 - Elsevier
Background Cytokine storm is the exaggerated immune response often observed in viral
infections. It is also intimately linked with the progression of COVID-19 disease as well as …

The role of N-methyl-D-aspartate glutamate receptors in Alzheimer's disease: From pathophysiology to therapeutic approaches

W Liu, Y Li, T Zhao, M Gong, X Wang, Y Zhang… - Progress in …, 2023 - Elsevier
N-Methyl-D-aspartate glutamate receptors (NMDARs) are involved in multiple
physiopathological processes, including synaptic plasticity, neuronal network activities …

Medicinal herbs with anti-inflammatory activities for natural and organic healing

MH Shahrajabian - Current Organic Chemistry, 2021 - benthamdirect.com
One of the principal causes of different disorders is an uncontrolled inflammatory response.
Alkaloids, flavonoids, polyphenolic, proanthocyanidin, terpenoid, and steroid compounds …

Spotlight on pro-inflammatory chemokines: regulators of cellular communication in cognitive impairment

C Wang, J Wang, Z Zhu, J Hu, Y Lin - Frontiers in Immunology, 2024 - frontiersin.org
Cognitive impairment is a decline in people's ability to think, learn, and remember, and so
forth. Cognitive impairment is a global health challenge that affects the quality of life of …

The role of CCR5 in HIV-associated neurocognitive disorders

C Riviere-Cazaux, J Cornell, Y Shen, M Zhou - Heliyon, 2022 - cell.com
While combination antiretroviral therapy (cART) has successfully increased the lifespan of
individuals infected with HIV, a significant portion of this population remains affected by HIV …

[HTML][HTML] Exploring the molecular mechanism of Yinao Fujian formula on ischemic stroke based on network pharmacology and experimental verification

J Lu, X Tang, Y Zhang, H Chu, C Jing, Y Wang, H Lou… - Heliyon, 2024 - cell.com
Background Ischemic stroke (IS) is a leading cause of long-term disability and even
mortality, threatening people's lives. Yinao Fujian (YNFJ) formula is a Traditional Chinese …

Metabolomic analysis of vascular cognitive impairment due to hepatocellular carcinoma

D Zhu, Y Zhu, L Liu, X He, S Fu - Frontiers in Neurology, 2023 - frontiersin.org
Introduction Screening for metabolically relevant differentially expressed genes (DEGs)
shared by hepatocellular carcinoma (HCC) and vascular cognitive impairment (VCI) to …

Potential therapeutic strategies to halt viral neuroinvasion

L Zhang, U Ashraf, H Chen, S Cao… - Reviews in Medical …, 2024 - Wiley Online Library
The viral infection of the central nervous system is a significant public health concern. So far,
most clinical cases of viral neuroinvasion are dealt with supportive and/or symptomatic …

Chemokine CCL2 impairs spatial memory and cognition in rats via influencing inflammation, glutamate metabolism and apoptosis-associated genes expression-a …

J Chen, L Tan, Y Liao, J Long, Y Zhou, J Wei, Y Zhou - Life Sciences, 2020 - Elsevier
Aims To explore the role of chemokine CC motif ligand 2 (CCL2) in spatial memory and
cognition impairment, and the underlying mechanisms focused on inflammatory, glutamate …

NMDA receptor antagonists engender neuroprotection against gp120‐induced cognitive dysfunction in rats through modulation of PKR activation, oxidative stress, ER …

Y Zeng, L Wang, Y Zhou, M Liang, J Yu… - European Journal of …, 2022 - Wiley Online Library
It is widely accepted that the surface glycoprotein (gp120) of human immunodeficiency virus‐
1 (HIV‐1) plays an important role in HIV‐1‐induced nerve damage and pathogenesis of HIV …