Emergent properties of dense DNA phases toward artificial biosystems on a surface
Conspectus The expression of genes in a cell in response to external signals or internal
programs occurs within an environment that is compartmentalized and dense …
programs occurs within an environment that is compartmentalized and dense …
Programming multi-protein assembly by gene-brush patterns and two-dimensional compartment geometry
O Vonshak, Y Divon, S Förste, D Garenne… - Nature …, 2020 - nature.com
The assembly of protein machines in cells is precise, rapid, and coupled to protein synthesis
with regulation in space and time. The assembly of natural and synthetic nanomachines …
with regulation in space and time. The assembly of natural and synthetic nanomachines …
Cell-free protein synthesis and assembly on a biochip
Biologically active complexes such as ribosomes and bacteriophages are formed through
the self-assembly of proteins and nucleic acids,. Recapitulating these biological self …
the self-assembly of proteins and nucleic acids,. Recapitulating these biological self …
Direct visualization of conformation and dense packing of DNA-based soft colloids
J Zhang, PM Lettinga, JKG Dhont, E Stiakakis - Physical review letters, 2014 - APS
Soft colloids—such as polymer-coated particles, star polymers, block-copolymer micelles,
microgels—constitute a broad class of materials where microscopic properties such as …
microgels—constitute a broad class of materials where microscopic properties such as …
Compartmentalization by directional gene expression
The coalescence of basic biochemical reactions into compartments is a major hallmark of a
living cell. Using surface-bound DNA and a transcription reaction, we investigate the …
living cell. Using surface-bound DNA and a transcription reaction, we investigate the …
Flexible control of cellular encapsulation, permeability, and release in a droplet-templated bifunctional copolymer scaffold
Q Chen, D Chen, J Wu, JM Lin - Biomicrofluidics, 2016 - pubs.aip.org
Designing cell-compatible, bio-degradable, and stimuli-responsive hydrogels is very
important for biomedical applications in cellular delivery and micro-scale tissue engineering …
important for biomedical applications in cellular delivery and micro-scale tissue engineering …
Spatially resolved DNA brushes on a chip: gene activation by enzymatic cascade
M Bar, RH Bar-Ziv - Nano letters, 2009 - ACS Publications
We assemble on a chip spatially resolved DNA polymer brushes with density that can be
controlled along continuous gradients, from dilute to dense packing, with 20− 30 nm …
controlled along continuous gradients, from dilute to dense packing, with 20− 30 nm …
DNA hybridization in thermoresponsive polymer nanoparticles
The detection of specific single-stranded DNA sequences by hybridization with the
corresponding complementary DNA probe is of fundamental importance in medical …
corresponding complementary DNA probe is of fundamental importance in medical …
Cell-free immuno-profiling on a genetically programmed biochip
A Dupin, O Vonshak, V Arad, M Levanon, N Avidan… - bioRxiv, 2024 - biorxiv.org
Emerging cell-free synthetic biology approaches provide biosafe, cheap, and versatile
genetic tools to advance therapeutic research and development. Combined with micro …
genetic tools to advance therapeutic research and development. Combined with micro …
Autonomous biogenesis of the entire protein translation machinery excluding ribosomes
M Schwarz-Schilling, A Dupin, N Avidan, Y Barak… - bioRxiv, 2024 - biorxiv.org
Recreating the conditions for autonomous biogenesis of the protein translation machinery is
fundamental to our understanding of living systems and is essential for the assembly of …
fundamental to our understanding of living systems and is essential for the assembly of …