The genetic architecture of quantitative traits

TFC Mackay - Annual review of genetics, 2001 - annualreviews.org
▪ Abstract Phenotypic variation for quantitative traits results from the segregation of alleles at
multiple quantitative trait loci (QTL) with effects that are sensitive to the genetic, sexual, and …

Evolutionary biology of animal cognition

R Dukas - Annu. Rev. Ecol. Evol. Syst., 2004 - annualreviews.org
▪ Abstract This review focuses on five key evolutionary issues pertaining to animal cognition,
defined as the neuronal processes concerned with the acquisition, retention, and use of …

Sex-specific genetic variance and the evolution of sexual dimorphism: a systematic review of cross-sex genetic correlations

J Poissant, AJ Wilson, DW Coltman - Evolution, 2010 - academic.oup.com
The independent evolution of the sexes may often be constrained if male and female
homologous traits share a similar genetic architecture. Thus, cross-sex genetic covariance is …

The X chromosome is a hot spot for sexually antagonistic fitness variation

JR Gibson, AK Chippindale… - Proceedings of the …, 2002 - royalsocietypublishing.org
Sexually antagonistic alleles are selected discordantly between the sexes. Experimental
evidence indicates that sexually antagonistic fitness variation is abundant in the genome of …

Functional dissection of Odorant binding protein genes in Drosophila melanogaster

S Swarup, TI Williams… - Genes, Brain and Behavior, 2011 - Wiley Online Library
Most organisms rely on olfaction for survival and reproduction. The olfactory system of
Drosophila melanogaster is one of the best characterized chemosensory systems and …

Sex-specific quantitative trait loci affecting longevity in Drosophila melanogaster

SV Nuzhdin, EG Pasyukova, CL Dilda… - Proceedings of the …, 1997 - National Acad Sciences
Senescence, the decline in survivorship and fertility with increasing age, is a near-universal
property of organisms. Senescence and limited lifespan are thought to arise because weak …

Quantitative genetic analyses of complex behaviours in Drosophila

RRH Anholt, TFC Mackay - Nature Reviews Genetics, 2004 - nature.com
Behaviours are exceptionally complex quantitative traits. Sensitivity to environmental
variation and genetic background, the presence of sexual dimorphism, and the widespread …

Analysis of natural variation reveals neurogenetic networks for Drosophila olfactory behavior

S Swarup, W Huang, TFC Mackay… - Proceedings of the …, 2013 - National Acad Sciences
Understanding the relationship between genetic variation and phenotypic variation for
quantitative traits is necessary for predicting responses to natural and artificial selection and …

The Genetic Basis for Variation in Olfactory Behavior in Drosophila melanogaster

GH Arya, MM Magwire, W Huang… - Chemical …, 2015 - academic.oup.com
The genetic underpinnings that contribute to variation in olfactory perception are not fully
understood. To explore the genetic basis of variation in olfactory perception, we measured …

Genetic interactions between naturally occuning alleles at quantitative trait loci and mutant alleles at candidate loci affecting bristle number in Drosophila …

AD Long, SL Mullaney, TFC Mackay, CH Langley - Genetics, 1996 - academic.oup.com
Previously, we mapped quantitative trait loci (QTL) affecting response to short-term selection
for abdominal bristle number to seven suggestive regions that contain loci involved in bristle …