The role of the epididymis and the contribution of epididymosomes to mammalian reproduction
It is well-established that testicular spermatozoa are immature and acquire motility and
fertilization capabilities during transit throughout the epididymis. The epididymis is a duct …
fertilization capabilities during transit throughout the epididymis. The epididymis is a duct …
Host specificity of the gut microbiome
EK Mallott, KR Amato - Nature Reviews Microbiology, 2021 - nature.com
Developing general principles of host–microorganism interactions necessitates a robust
understanding of the eco-evolutionary processes that structure microbiota. Phylosymbiosis …
understanding of the eco-evolutionary processes that structure microbiota. Phylosymbiosis …
Placental origins of chronic disease
Epidemiological evidence links an individual's susceptibility to chronic disease in adult life to
events during their intrauterine phase of development. Biologically this should not be …
events during their intrauterine phase of development. Biologically this should not be …
Local immune recognition of trophoblast in early human pregnancy: controversies and questions
A Moffett, N Shreeve - Nature Reviews Immunology, 2023 - nature.com
The role of the maternal immune system in reproductive success in humans remains
controversial. Here we focus on the events that occur in the maternal decidua during the first …
controversial. Here we focus on the events that occur in the maternal decidua during the first …
The placental mammal ancestor and the post–K-Pg radiation of placentals
To discover interordinal relationships of living and fossil placental mammals and the time of
origin of placentals relative to the Cretaceous-Paleogene (K-Pg) boundary, we scored 4541 …
origin of placentals relative to the Cretaceous-Paleogene (K-Pg) boundary, we scored 4541 …
Placenta: the forgotten organ
E Maltepe, SJ Fisher - Annual review of cell and developmental …, 2015 - annualreviews.org
The placenta sits at the interface between the maternal and fetal vascular beds where it
mediates nutrient and waste exchange to enable in utero existence. Placental cells …
mediates nutrient and waste exchange to enable in utero existence. Placental cells …
Single-cell transcriptomics of the human placenta: inferring the cell communication network of the maternal-fetal interface
Organismal function is, to a great extent, determined by interactions among their
fundamental building blocks, the cells. In this work, we studied the cell-cell interactome of …
fundamental building blocks, the cells. In this work, we studied the cell-cell interactome of …
The human placenta: new perspectives on its formation and function during early pregnancy
GJ Burton, E Jauniaux - Proceedings of the Royal Society …, 2023 - royalsocietypublishing.org
The placenta has evolved to support the development of the embryo and fetus during the
different intrauterine periods of life. By necessity, its development must precede that of the …
different intrauterine periods of life. By necessity, its development must precede that of the …
Role of macrophages in pregnancy and related complications
Macrophages (MФs) are the leukocytes produced from differentiation of monocytes and are
located in almost all tissues of human body. They are involved in various processes, such as …
located in almost all tissues of human body. They are involved in various processes, such as …
Serum microRNAs are promising novel biomarkers
S Gilad, E Meiri, Y Yogev, S Benjamin, D Lebanony… - PloS one, 2008 - journals.plos.org
Background Circulating nucleic acids (CNAs) offer unique opportunities for early diagnosis
of clinical conditions. Here we show that microRNAs, a family of small non-coding regulatory …
of clinical conditions. Here we show that microRNAs, a family of small non-coding regulatory …