Abstract Purpose of Review To review the role of the immune cells and their interaction with
cells found in gingiva, periodontal ligament, and bone that leads to net bone loss in …

Sensing the mechanical properties of the substrates or the matrix by the cells and the
tissues, the subsequent downstream responses at the cellular, nuclear and epigenetic levels …

Alveolar bone remodeling in orthodontic tooth movement (OTM) is a highly regulated
process that coordinates bone resorption by osteoclasts and new bone formation by …

Exosomes play a critical role in intracellular communication. The biogenesis and function of
exosomes are regulated by multiple biochemical factors. In the present study, we find that …

Background Superimposition of three-dimensional (3D) digital models offers great
opportunities to assess tooth movement during time. In the literature, several …

Clinical evidence indicates that in physiological and therapeutic conditions a continuous
remodeling of the tooth root cementum and the periodontal apparatus is required to maintain …

Introduction External apical root resorption is nearly ubiquitous in people treated
orthodontically. This study predicted the extent of external apical root resorption by the …

Animal experiments are essential for the elucidation of biological-cellular mechanisms in the
context of orthodontic tooth movement (OTM). So far, however, no studies comparatively …

Background The role of periodontal ligament stem cells (PDLSCs) and macrophage
polarization in periodontal tissue regeneration and bone remodeling during orthodontic …

Background Oral health is of fundamental importance to maintain systemic health in
humans. Stem cell-based oral tissue regeneration is a promising strategy to achieve the …