Magnetic graphene oxide: synthesis approaches, physicochemical characteristics, and biomedical applications

Y He, C Yi, X Zhang, W Zhao, D Yu - TrAC Trends in Analytical Chemistry, 2021 - Elsevier
Magnetic graphene oxide, a compound of magnetic nanoparticles and graphene oxide,
possesses distinct physical and chemical characteristics, including nano size, a large …

Biomaterial-mediated internal radioisotope therapy

P Pei, T Liu, W Shen, Z Liu, K Yang - Materials Horizons, 2021 - pubs.rsc.org
Radiation therapy (RT), including external beam radiotherapy (EBRT) and internal
radioisotope therapy (RIT), has been an indispensable strategy for cancer therapy in clinical …

[HTML][HTML] A perspective on the radiopharmaceutical requirements for imaging and therapy of glioblastoma

J Bolcaen, J Kleynhans, S Nair, J Verhoeven… - Theranostics, 2021 - ncbi.nlm.nih.gov
Despite numerous clinical trials and pre-clinical developments, the treatment of glioblastoma
(GB) remains a challenge. The current survival rate of GB averages one year, even with an …

Targeted Radionuclide Therapy in Glioblastoma

X Zhao, V Jakobsson, Y Tao, T Zhao… - … Applied Materials & …, 2024 - ACS Publications
Despite the development of various novel therapies, glioblastoma (GBM) remains a
devastating disease, with a median survival of less than 15 months. Recently, targeted …

Delivery systems exploiting natural cell transport processes of macromolecules for intracellular targeting of Auger electron emitters

AA Rosenkranz, TA Slastnikova, GP Georgiev… - Nuclear Medicine and …, 2020 - Elsevier
The presence of Auger electrons (AE) among the decay products of a number of
radionuclides makes these radionuclides an attractive means for treating cancer because …

Polyoxomolybdate (POM) nanoclusters with radiosensitizing and scintillating properties for low dose X-ray inducible radiation-radiodynamic therapy

D Maiti, J Zhong, Z Zhang, H Zhou, S Xion… - Nanoscale …, 2020 - pubs.rsc.org
In order to overcome the weak penetration of near infrared (NIR) light in photodynamic
therapy (PDT), X-ray radiation (X-RT) with high deep tissue penetration could be used as a …

Advancements in the use of Auger electrons in science and medicine during the period 2015–2019

RW Howell - International journal of radiation biology, 2023 - Taylor & Francis
Auger electrons can be highly radiotoxic when they are used to irradiate specific molecular
sites. This has spurred basic science investigations of their radiobiological effects and …

[HTML][HTML] Remote loading of liposomes with a 124I-radioiodinated compound and their in vivo evaluation by PET/CT in a murine tumor model

G Engudar, H Schaarup-Jensen, FP Fliedner… - Theranostics, 2018 - ncbi.nlm.nih.gov
Long circulating liposomes entrapping iodinated and radioiodinated compounds offer a
highly versatile theranostic platform. Here we report a new methodology for efficient and …

[HTML][HTML] Auger radiopharmaceutical therapy targeting prostate-specific membrane antigen in a micrometastatic model of prostate cancer

CJ Shen, I Minn, RF Hobbs, Y Chen, A Josefsson… - Theranostics, 2020 - ncbi.nlm.nih.gov
Auger radiopharmaceutical therapy is a promising strategy for micrometastatic disease
given high linear energy transfer and short range in tissues, potentially limiting normal tissue …

Convection-enhanced drug delivery for glioblastoma: A systematic review focused on methodological differences in the use of the convection-enhanced delivery …

B Halle, K Mongelard, F Poulsen - Asian Journal of …, 2019 - thieme-connect.com
Glioblastoma (GBM) is a leading cause of brain cancer-related death. The blood–brain
barrier (BBB) prevents the transport of most systemic delivered molecules to the brain. This …