[HTML][HTML] Artificial intelligence in retina

U Schmidt-Erfurth, A Sadeghipour, BS Gerendas… - Progress in retinal and …, 2018 - Elsevier
Major advances in diagnostic technologies are offering unprecedented insight into the
condition of the retina and beyond ocular disease. Digital images providing millions of …

Neovascular age-related macular degeneration: therapeutic management and new-upcoming approaches

F Ricci, F Bandello, P Navarra, G Staurenghi… - International journal of …, 2020 - mdpi.com
Age-related macular degeneration (AMD) constitutes a prevalent, chronic, and progressive
retinal degenerative disease of the macula that affects elderly people and cause central …

Efficacy, durability, and safety of intravitreal faricimab up to every 16 weeks for neovascular age-related macular degeneration (TENAYA and LUCERNE): two …

JS Heier, AM Khanani, CQ Ruiz, K Basu, PJ Ferrone… - The Lancet, 2022 - thelancet.com
Background Faricimab is a bispecific antibody that acts through dual inhibition of both
angiopoietin-2 and vascular endothelial growth factor A. We report primary results of two …

Tolerating subretinal fluid in neovascular age-related macular degeneration treated with ranibizumab using a treat-and-extend regimen: FLUID study 24-month results

RH Guymer, CM Markey, IL McAllister, MC Gillies… - Ophthalmology, 2019 - Elsevier
Purpose To test the hypothesis that tolerating some subretinal fluid (SRF) in patients with
neovascular age-related macular degeneration (nAMD) treated with ranibizumab using a …

Efficacy and safety of intravitreal aflibercept treat-and-extend regimens in exudative age-related macular degeneration: 52-and 96-week findings from ALTAIR: a …

M Ohji, K Takahashi, AA Okada, M Kobayashi… - Advances in …, 2020 - Springer
Purpose To evaluate efficacy and safety of intravitreal injections of aflibercept (IVT-AFL) treat-
and-extend (T&E) dosing regimens in treatment-naïve patients with exudative age-related …

[HTML][HTML] HAWK and HARRIER: phase 3, multicenter, randomized, double-masked trials of brolucizumab for neovascular age-related macular degeneration

PU Dugel, A Koh, Y Ogura, GJ Jaffe, U Schmidt-Erfurth… - Ophthalmology, 2020 - Elsevier
Purpose Two similarly designed phase 3 trials (HAWK and HARRIER) compared
brolucizumab, a single-chain antibody fragment that inhibits vascular endothelial growth …

RETOUCH: The retinal OCT fluid detection and segmentation benchmark and challenge

H Bogunović, F Venhuizen, S Klimscha… - IEEE transactions on …, 2019 - ieeexplore.ieee.org
Retinal swelling due to the accumulation of fluid is associated with the most vision-
threatening retinal diseases. Optical coherence tomography (OCT) is the current standard of …

Artificial intelligence promotes the diagnosis and screening of diabetic retinopathy

X Huang, H Wang, C She, J Feng, X Liu, X Hu… - Frontiers in …, 2022 - frontiersin.org
Deep learning evolves into a new form of machine learning technology that is classified
under artificial intelligence (AI), which has substantial potential for large-scale healthcare …

[HTML][HTML] AI-based monitoring of retinal fluid in disease activity and under therapy

U Schmidt-Erfurth, GS Reiter, S Riedl… - Progress in retinal and …, 2022 - Elsevier
Retinal fluid as the major biomarker in exudative macular disease is accurately visualized by
high-resolution three-dimensional optical coherence tomography (OCT), which is used …

Ranibizumab treatment in treatment-naive neovascular age-related macular degeneration: results from LUMINOUS, a global real-world study

FG Holz, MS Figueroa, F Bandello, Y Yang, M Ohji… - Retina, 2020 - journals.lww.com
Purpose: To evaluate the effectiveness, safety, and treatment patterns of ranibizumab 0.5 mg
in treatment-naive patients with neovascular age-related macular degeneration enrolled in …