Calcium ions generate versatile intracellular signals that control key functions in all types of
neurons. Imaging calcium in neurons is particularly important because calcium signals exert …

Natural odors, generally composed of many monomolecular components, are analyzed by
peripheral receptors into component features and translated into spatiotemporal patterns of …

Spiking neural networks (SNNs) promise to bridge the gap between artificial neural
networks (ANNs) and biological neural networks (BNNs) by exploiting biologically plausible …

Functional hyperemia, a regional increase of blood flow triggered by local neural activation,
is used to map brain activity in health and disease. However, the spatial-temporal dynamics …

Two-photon calcium imaging is a powerful means for monitoring the activity of distinct
neurons in brain tissue in vivo. In the mammalian brain, such imaging studies have been …

A recurrent idea in the study of complex systems is that optimal information processing is to
be found near phase transitions. However, this heuristic hypothesis has few (if any) concrete …

Olfactory perception is initiated by the recognition of odorants by a large repertoire of
receptors in the sensory epithelium. A dispersed pattern of neural activity in the nose is …

An understanding of the logic of odor perception requires a functional analysis of odor-
evoked patterns of activity in neural assemblies in the brain. We have developed a sensitive …

The properties of cortical circuits underlying central representations of sensory stimuli are
poorly understood. Here we use in vivo cell-attached and whole-cell voltage-clamp …

The olfactory system's ability to detect and discriminate between the vast array of chemicals
present in the environment is critical for an animal's survival. In mammals, the first step of this …