Obesity and heart failure with preserved ejection fraction (HFpEF) represent two
intermingling epidemics driving perhaps the greatest unmet health problem in …

Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous entity with
complex pathophysiology and manifestations. Phenomapping is the process of applying …

Background Obesity increases the risk of heart failure with preserved ejection fraction.
Tirzepatide, a long-acting agonist of glucose-dependent insulinotropic polypeptide and …

Aims Although body mass index (BMI) is the most commonly used anthropometric measure,
newer indices such as the waist-to-height ratio, better reflect the location and amount of …

Aims We aimed to derive and validate clinically useful clusters of patients with heart failure
with preserved ejection fraction (HFpEF; left ventricular ejection fraction≥ 50%). Methods …

Traditional diagnosis and understanding of the pathophysiology of obesity are based on
excessive fat storage due to a chronically positive energy balance characterized by body …

Heart failure (HF) with preserved ejection (HFpEF) constitutes a large and growing
proportion of patients with HF around the world, and is now responsible for more than half of …

Currently, South Asia accounts for a quarter of the world population, yet it already claims≈
60% of the global burden of heart disease. Besides the epidemics of type 2 diabetes mellitus …

Aims In heart failure with reduced ejection fraction (HFrEF), there is an 'obesity paradox',
where survival is better in patients with a higher body mass index (BMI) and weight loss is …

Background Obesity, a known risk factor for cardiovascular disease and heart failure (HF), is
associated with adverse cardiac remodeling in the general population. Little is known about …