Nowadays, diabetes mellitus has emerged as a significant global public health concern with
a remarkable increase in its prevalence. This review article focuses on the definition of …

SARS-CoV-2 causes an acute respiratory tract infection that resolves in most people in less
than a month. Yet some people with severely weakened immune systems fail to clear the …

Bullous pemphigoid (BP) is an autoimmune blistering skin disease characterized by intense
itching and tense fluid-filled bullae and erythema located typically on the trunk and …

A wide variety of immunomodulatory therapies are already available for the treatment of
multiple sclerosis (MS). Through fundamental insights from basic research with a gain of …

Systemic sclerosis is a connective tissue disease of unknown origin and with an
unpredictable course, with both cutaneous and internal organ manifestations. Despite the …

Background Type 1 diabetes mellitus (T1DM) may be associated with various autoimmune
diseases, but the causal relationship between T1DM and autoimmune skin diseases is not …

Background CD20+ T cells represent up to 5% of circulating T lymphocytes. These cells
have been shown to produce higher levels of IL-17A and IFN-γ than those of CD20− T …

Ferroptosis resistance is vital for B cell development, especially in inflammatory diseases,
yet the underlying mechanism is still unclear. In this study, based on the scRNA‐seq …

Pemphigus, an autoimmune blistering disorder, poses significant therapeutic challenges
due to dysregulated B cells and the involvement of CD20. This review assesses the efficacy …

Monoclonal antibodies (mAbs) have revolutionised modern medicine due to their ability to
treat a wide range of diseases, including cancer, autoimmune diseases and infectious …