Implications of insulin-like growth factor-1 in skeletal muscle and various diseases

SS Ahmad, K Ahmad, EJ Lee, YH Lee, I Choi - Cells, 2020 - mdpi.com
Skeletal muscle is an essential tissue that attaches to bones and facilitates body
movements. Insulin-like growth factor-1 (IGF-1) is a hormone found in blood that plays an …

Potential therapeutic strategies for skeletal muscle atrophy

L Huang, M Li, C Deng, J Qiu, K Wang, M Chang… - Antioxidants, 2022 - mdpi.com
The maintenance of muscle homeostasis is vital for life and health. Skeletal muscle atrophy
not only seriously reduces people's quality of life and increases morbidity and mortality, but …

Diabetic muscular atrophy: molecular mechanisms and promising therapies

Y Shen, M Li, K Wang, G Qi, H Liu, W Wang… - Frontiers in …, 2022 - frontiersin.org
Diabetes mellitus (DM) is a typical chronic disease that can be divided into 2 types,
dependent on insulin deficiency or insulin resistance. Incidences of diabetic complications …

The impact of glucose-lowering drugs on sarcopenia in type 2 diabetes: current evidence and underlying mechanisms

E Massimino, A Izzo, G Riccardi, G Della Pepa - Cells, 2021 - mdpi.com
The age-related decrease in skeletal muscle mass together with the loss of muscle power
and function is defined sarcopenia. Mounting evidence suggests that the prevalence of …

Role of hormones in sarcopenia

T Priego, AI Martín, D González-Hedström… - Vitamins and …, 2021 - Elsevier
Aging involves numerous changes in body composition that include a decrease in skeletal
muscle mass. The gradual reduction in muscle mass is associated with a simultaneous …

IGF-1 and IGFBP-3 in Inflammatory Cachexia

AI Martín, T Priego, Á Moreno-Ruperez… - International Journal of …, 2021 - mdpi.com
Inflammation induces a wide response of the neuroendocrine system, which leads to
modifications in all the endocrine axes. The hypothalamic–growth hormone (GH)–insulin …

Mechanisms involved in gut microbiota regulation of skeletal muscle

G Li, B Jin, Z Fan - Oxidative Medicine and Cellular Longevity, 2022 - Wiley Online Library
Skeletal muscle is one of the largest organs in the body and is essential for maintaining
quality of life. Loss of skeletal muscle mass and function can lead to a range of adverse …

Frailty in rheumatic diseases

F Motta, A Sica, C Selmi - Frontiers in immunology, 2020 - frontiersin.org
Frailty is a syndrome characterized by the decline in the physiologic reserve and function of
several systems, leading to increased vulnerability and adverse health outcomes. While …

Physical Exercise as Disease-Modifying Alternative against Alzheimer's Disease: A Gut–Muscle–Brain Partnership

D Cutuli, D Decandia, G Giacovazzo… - International journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is a common cause of dementia characterized by
neurodegenerative dysregulations, cognitive impairments, and neuropsychiatric symptoms …

[HTML][HTML] The roles of growth factors and hormones in the regulation of muscle satellite cells for cultured meat production

SS Ahmad, HJ Chun, K Ahmad, S Shaikh… - Journal of Animal …, 2023 - ncbi.nlm.nih.gov
Cultured meat is a potential sustainable food generated by the in vitro myogenesis of muscle
satellite (stem) cells (MSCs). The self-renewal and differentiation properties of MSCs are of …