Therapeutic effects of medicinal plants and their constituents on lung cancer, in vitro, in vivo and clinical evidence

A Memarzia, S Saadat, F Asgharzadeh… - Journal of Cellular …, 2023 - Wiley Online Library
The most common type of cancer in the world is lung cancer. Traditional treatments have an
important role in cancer therapy. In the present review, the most recent findings on the …

Targeting PPARs for therapy of atherosclerosis: A review

M Miao, X Wang, T Liu, YJ Li, WQ Yu, TM Yang… - International journal of …, 2023 - Elsevier
Atherosclerosis, a chief pathogenic factor of cardiovascular disease, is associated with many
factors including inflammation, dyslipidemia, and oxidative stress. Peroxisome proliferator …

The effects of Crocus sativus extract on inhaled paraquat-induced lung inflammation, oxidative stress, pathological changes and tracheal responsiveness in rats

A Memarzia, SZ Ghasemi, S Behrouz, MH Boskabady - Toxicon, 2023 - Elsevier
Paraquat is a green liquid toxin that is used in agriculture and can induce multi-organ
including lung injury. Various pharmacological effects of Crocus sativus (C. sativus) were …

The Effect of Curcuma longa on Inflammatory Mediators and Immunological, Oxidant, and Antioxidant Biomarkers in Asthmatic Rats

MH Boskabady, F Amin… - … Based Complementary and …, 2021 - Wiley Online Library
The effects of Curcuma longa (C. longa) on total and differential WBC, inflammatory and
immunologic mediators, and oxidant and antioxidant biomarkers in bronchoalveolar lavage …

[HTML][HTML] Andrographolide alleviates paraquat-induced acute lung injury by activating the Nrf2/HO-1 pathway

D Zhang, F Shen, S Ma, S Nan, Y Ma… - Iranian Journal of …, 2023 - ncbi.nlm.nih.gov
Objective (s): Paraquat (PQ), a highly effective and rapidly non-selective herbicide, mainly
targets the lungs and causes acute lung injury (ALI). So far, the scarcity of effective drug …

Paraquat-induced systemic inflammation and oxidative stress in rats improved by Curcuma longa ethanolic extract, curcumin and a PPAR agonist

SZ Ghasemi, S Beigoli, A Memarzia, S Behrouz… - Toxicon, 2023 - Elsevier
The effect of Curcuma longa (Cl) ethanolic extract, nano-curcumin (Cu) and a PPARγ
activator, pioglitazone on inhaled paraquat (PQ)-induced systemic inflammation and …

Systemic and Lung Inflammation and Oxidative Stress Associated With Behavioral Changes Induced by Inhaled Paraquat Are Ameliorated by Carvacrol

A Memarzia, F Amin, A Mokhtari-Zaer, Z Arab… - PPAR …, 2024 - Wiley Online Library
Paraquat (PQ) is an herbicide toxin that induces injury in different organs. The anti‐
inflammatory and antioxidant effects of carvacrol were reported previously. The effects of …

The preventive effectiveness of Crocus sativus extract in treating lung injuries caused by inhaled paraquat in rats

A Memarzia, S Beigoli, MHE Ghalibaf… - Journal of …, 2025 - Elsevier
Ethnopharmacological relevance The herbicide paraquat (PQ) is highly toxic, capable of
inducing severe lung inflammation and oxidative stress, resulting in lung fibrosis and …

[HTML][HTML] Effects of Crocus sativus and its constituent, safranal, and pioglitazone, on systemic inflammation and oxidative stress induced by paraquat aerosol in rats

A Memarzia, SZ Ghasemi, F Amin… - Iranian Journal of …, 2024 - ncbi.nlm.nih.gov
Objective (s): The effects of Crocus sativus, safranal, and pioglitazone on aerosolized
paraquat (PQ)-induced systemic changes were examined. Materials and Methods: Control …

[HTML][HTML] Curcuma longa alone and in combination with pioglitazone attenuates paraquat-induced lung injury in rats through improving inflammation, oxidative stress …

SZ Ghasemi, S Beigoli, S Behrouz… - Journal of Traditional …, 2023 - Elsevier
Background and aim The therapeutic effects of pioglitazone (Pio), dexamethasone (Dexa)
and Curcuma longa (Cl) on inhaled paraquat (PQ)-induced lung oxidative stress …