Andrographolide: A review of its pharmacology, pharmacokinetics, toxicity and clinical trials and pharmaceutical researches

B Zeng, A Wei, Q Zhou, M Yuan, K Lei… - Phytotherapy …, 2022 - Wiley Online Library
Abstract Andrographis paniculata (Burm. f.) Wall. ex Nees, a renowned herb medicine in
China, is broadly utilized in traditional Chinese medicine (TCM) for the treatment of cold and …

Andrographolide, a natural antioxidant: An update

E Mussard, A Cesaro, E Lespessailles, B Legrain… - Antioxidants, 2019 - mdpi.com
Traditionally, Andrographis paniculata has been used as an herbal remedy for lung infection
treatments. Its leaves contain a diterpenoid labdane called andrographolide responsible for …

Anti-SARS-CoV-2 Activity of Andrographis paniculata Extract and Its Major Component Andrographolide in Human Lung Epithelial Cells and Cytotoxicity Evaluation …

K Sa-Ngiamsuntorn, A Suksatu… - Journal of natural …, 2021 - ACS Publications
The coronaviruses disease 2019 (COVID-19) caused by a novel coronavirus (SARS-CoV-2)
has become a major health problem, affecting more than 50 million people with over one …

Medicinal plants used against hepatic disorders in Bangladesh: a comprehensive review

R Das, S Mitra, AM Tareq, TB Emran… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Liver disease is a major cause of illness and death
worldwide which accounts for approximately 2 million deaths per year worldwide, 1 million …

Broad-spectrum antiviral properties of andrographolide

S Gupta, KP Mishra, L Ganju - Archives of virology, 2017 - Springer
Andrographolide, a diterpenoid, is known for its anti-inflammatory effects. It can be isolated
from various plants of the genus Andrographis, commonly known as 'creat'. This purified …

Hepatoprotective potential of Malaysian medicinal plants: a review on phytochemicals, oxidative stress, and antioxidant mechanisms

BA Venmathi Maran, M Iqbal, P Gangadaran, BC Ahn… - Molecules, 2022 - mdpi.com
Hepatotoxicity is a major global public health concern. Despite advances in modern
medicine, the demerits of chemically prepared drugs outweigh their merits. In addition, the …

Antioxidant effects of catechins (EGCG), andrographolide, and curcuminoids compounds for skin protection, cosmetics, and dermatological uses: an update

G Messire, R Serreau, S Berteina-Raboin - Antioxidants, 2023 - mdpi.com
Here we have chosen to highlight the main natural molecules extracted from Camellia
sinensis, Andrographis paniculata, and Curcuma longa that may possess antioxidant …

A comprehensive overview of hepatoprotective natural compounds: mechanism of action and clinical perspectives

R Domitrović, I Potočnjak - Archives of toxicology, 2016 - Springer
Hepatoprotective effects of natural compounds have been frequently attributed to their
antioxidant properties and the ability to mobilize endogenous antioxidant defense system …

The role of nuclear factor erythroid 2-related factor 2 in hepatoprotective activity of natural products: a review

M Iranshahy, M Iranshahi, SR Abtahi… - Food and Chemical …, 2018 - Elsevier
Internal metabolism and environmental toxicant exposure can be caused to generate
reactive oxygen species in human organelles which lead to oxidative stress. The nuclear …

Andrographolide ameliorates oxidative stress, inflammation and histological outcome in complete Freund's adjuvant-induced arthritis

S Luo, H Li, J Liu, X Xie, Z Wan, Y Wang, Z Zhao… - Chemico-biological …, 2020 - Elsevier
Objectives As one of the main active ingredients of Chinese herbal medicine Andrographis
paniculate, andrographolide is used in domestic clinical treatment for respiratory infections …