Mesenchymal stem cell secretome: toward cell-free therapeutic strategies in regenerative medicine

FJ Vizoso, N Eiro, S Cid, J Schneider… - International journal of …, 2017 - mdpi.com
Earlier research primarily attributed the effects of mesenchymal stem cell (MSC) therapies to
their capacity for local engrafting and differentiating into multiple tissue types. However …

The impact of sensory neuropathy and inflammation on epithelial wound healing in diabetic corneas

XY Fu-Shin, PSY Lee, L Yang, N Gao, Y Zhang… - Progress in retinal and …, 2022 - Elsevier
Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes, with
several underlying pathophysiological mechanisms, some of which are still uncertain. The …

Current understanding of hydrogel for drug release and tissue engineering

L Lei, Y Bai, X Qin, J Liu, W Huang, Q Lv - Gels, 2022 - mdpi.com
Due to their good absorption, satisfactory biocompatibility, and high safety, hydrogels have
been widely used in the field of biomedicine, including for drug delivery and tissue …

Progress in corneal wound healing

AV Ljubimov, M Saghizadeh - Progress in retinal and eye research, 2015 - Elsevier
Corneal wound healing is a complex process involving cell death, migration, proliferation,
differentiation, and extracellular matrix remodeling. Many similarities are observed in the …

Myofibroblasts

B Hinz - Experimental eye research, 2016 - Elsevier
Myofibroblasts are activated in response to tissue injury with the primary task to repair lost or
damaged extracellular matrix. Enhanced collagen secretion and subsequent contraction …

Corneal stromal wound healing: Major regulators and therapeutic targets

S Kamil, RR Mohan - The ocular surface, 2021 - Elsevier
Corneal stromal wound healing is a complex event that occurs to restore the transparency of
an injured cornea. It involves immediate apoptosis of keratocytes followed by their activation …

The corneal fibrosis response to epithelial–stromal injury

AAM Torricelli, A Santhanam, J Wu, V Singh… - Experimental eye …, 2016 - Elsevier
The corneal wound healing response, including the development of stromal opacity in some
eyes, is a process that often leads to scarring that occurs after injury, surgery or infection to …

Biomechanics and wound healing in the cornea

WJ Dupps Jr, SE Wilson - Experimental eye research, 2006 - Elsevier
The biomechanical and wound healing properties of the cornea undermine the predictability
and stability of refractive surgery and contribute to discrepancies between attempted and …

Mechanistic investigations of diabetic ocular surface diseases

Q Zhou, L Yang, Q Wang, Y Li, C Wei… - Frontiers in …, 2022 - frontiersin.org
With the global prevalence of diabetes mellitus over recent decades, more patients suffered
from various diabetic complications, including diabetic ocular surface diseases that may …

Pathogenesis of pterygia: role of cytokines, growth factors, and matrix metalloproteinases

N Di Girolamo, J Chui, MT Coroneo… - Progress in retinal and …, 2004 - Elsevier
Pterygium is a common ocular surface disease apparently only observed in humans.
Chronic UV exposure is a widely accepted aetiological factor in the pathogenesis of this …