The impact of prenatal alcohol exposure on social, cognitive and affective behavioral domains: Insights from rodent models

K Marquardt, JL Brigman - Alcohol, 2016 - Elsevier
Abstract Fetal Alcohol Spectrum Disorders (FASD) are characterized by deficits in working
memory, response inhibition, and behavioral flexibility. However, the combination and …

Fetal exposure to teratogens: evidence of genes involved in autism

D Dufour-Rainfray, P Vourc'h, S Tourlet… - Neuroscience & …, 2011 - Elsevier
Environmental challenges during the prenatal period can result in behavioral abnormalities
and cognitive deficits that appear later in life such as autism. Prenatal exposure to valproic …

[HTML][HTML] The interaction of genetic sex and prenatal alcohol exposure on health across the lifespan

S Bake, SK Rouzer, S Mavuri, RC Miranda… - Frontiers in …, 2023 - Elsevier
Prenatal alcohol exposure (PAE) can reprogram the development of cells and tissues,
resulting in a spectrum of physical and neurobehavioral teratology. PAE immediately …

Role of microglia in ethanol-induced neurodegenerative disease: Pathological and behavioral dysfunction at different developmental stages

JY Yang, X Xue, H Tian, XX Wang, YX Dong… - Pharmacology & …, 2014 - Elsevier
Alcohol abuse can result in significant alterations to the structure of the brain and ultimately
to behavioral dysfunctions. Epidemiological studies have shown that alcoholism is closely …

Ethanol exposure induces neonatal neurodegeneration by enhancing CB1R Exon1 histone H4K8 acetylation and up-regulating CB1R function causing …

S Subbanna, NN Nagre, NS Umapathy… - International Journal …, 2015 - academic.oup.com
Background: Ethanol exposure to rodents during postnatal day 7 (P7), which is comparable
to the third trimester of human pregnancy, induces long-term potentiation and memory …

Neurotrophins in the brain: interaction with alcohol exposure during development

KE Boschen, AY Klintsova - Vitamins and hormones, 2017 - Elsevier
Fetal alcohol spectrum disorders (FASDs) are a result of the teratogenic effects of alcohol on
the developing fetus. Decades of research examining both individuals with FASDs and …

An examination of sex differences in the effects of early-life opiate and alcohol exposure

LS Terasaki, J Gomez… - … Transactions of the …, 2016 - royalsocietypublishing.org
Early-life exposure to drugs and alcohol is one of the most preventable causes of
developmental, behavioural and learning disorders in children. Thus a significant amount of …

Effects of moderate prenatal ethanol exposure and age on social behavior, spatial response perseveration errors and motor behavior

DA Hamilton, D Barto, CI Rodriguez… - Behavioural brain …, 2014 - Elsevier
Persistent deficits in social behavior are among the major negative consequences
associated with exposure to ethanol during prenatal development. Prior work from our …

Social interaction in adolescent rats with neonatal ethanol exposure: Impact of sex and CE-123, a selective dopamine reuptake inhibitor

J Socha, P Grochecki, I Smaga, J Jastrzębska… - International Journal of …, 2024 - mdpi.com
Children with fetal alcohol spectrum disorders (FASDs) demonstrate deficits in social
functioning that contribute to early withdrawal from school and delinquency, as well as the …

Effects of acute prenatal exposure to ethanol on microRNA expression are ameliorated by social enrichment

C Ignacio, SM Mooney, FA Middleton - Frontiers in pediatrics, 2014 - frontiersin.org
Fetal alcohol spectrum disorders (FASDs) are associated with abnormal social behavior.
These behavioral changes may resemble those seen in autism. Rats acutely exposed to …