Fiber-type shifting in sarcopenia of old age: proteomic profiling of the contractile apparatus of skeletal muscles

P Dowling, S Gargan, D Swandulla… - International Journal of …, 2023 - mdpi.com
The progressive loss of skeletal muscle mass and concomitant reduction in contractile
strength plays a central role in frailty syndrome. Age-related neuronal impairments are …

Interactions between muscle and bone—where physics meets biology

M Herrmann, K Engelke, R Ebert, S Müller-Deubert… - Biomolecules, 2020 - mdpi.com
Muscle and bone interact via physical forces and secreted osteokines and myokines.
Physical forces are generated through gravity, locomotion, exercise, and external devices …

The effects of resistance training on architecture and volume of the upper extremity muscles: a systematic review of randomised controlled trials and meta-analyses

G Yagiz, E Akaras, HP Kubis, JA Owen - Applied Sciences, 2022 - mdpi.com
To systematically review the effects of exercise on fascicle geometry and muscle size
parameters of the upper extremity muscles, the CENTRAL, CINAHL, PubMed and OpenGrey …

Multi-omic, single-cell, and biochemical profiles of astronauts guide pharmacological strategies for returning to gravity

ML Gertz, CR Chin, D Tomoiaga, M MacKay, C Chang… - Cell reports, 2020 - cell.com
Summary The National Aeronautics and Space Administration (NASA) Twins Study created
an integrative molecular profile of an astronaut during NASA's first 1-year mission on the …

[HTML][HTML] What can biofabrication do for space and what can space do for biofabrication?

L Moroni, K Tabury, H Stenuit, D Grimm, S Baatout… - Trends in …, 2022 - cell.com
Biofabrication in space is one of the novel promising and prospective research directions in
the rapidly emerging field of space STEM. There are several advantages of biofabrication in …

Implementation of exercise countermeasures during spaceflight and microgravity analogue studies: developing countermeasure protocols for bedrest in older adults …

ET Hedge, CA Patterson, CJ Mastrandrea… - Frontiers in …, 2022 - frontiersin.org
Significant progress has been made in the development of countermeasures to attenuate
the negative consequences of prolonged exposure to microgravity on astronauts' bodies …

Effects of bed rest on physical performance in athletes: A systematic and narrative review

BA Spiering, J Weakley, I Mujika - Sports Medicine, 2023 - Springer
Background Athletes can face scenarios in which they are confined to bed rest (eg, due to
injury or illness). Existing research in otherwise healthy individuals indicates that those …

Electromagnetic field induced alterations in fluid flow through lacuno-canalicular system of bone

R Kumar, AK Tiwari, D Tripathi, A Mishra - International Journal of …, 2022 - Elsevier
Osteoporosis, bone-muscle disuse, and long-term exposure to space microgravity cause
bone loss and promote bone fractures. Therapeutic devices and interventions for the …

Mammalian and invertebrate models as complementary tools for gaining mechanistic insight on muscle responses to spaceflight

T Cahill, H Cope, JJ Bass, EG Overbey… - International Journal of …, 2021 - mdpi.com
Bioinformatics approaches have proven useful in understanding biological responses to
spaceflight. Spaceflight experiments remain resource intensive and rare. One outstanding …

Analog and simulated microgravity platforms for life sciences research: Their individual capacities, benefits and limitations

FA Oluwafemi, A Neduncheran - Advances in Space Research, 2022 - Elsevier
Gravity is always present on Earth. However, the influence of gravity can be modified or
compensated. Generally, the products created under microgravity have important properties …