Glioblastoma multiforme is the most aggressive malignant tumor of the central nervous
system. Due to the absence of effective pharmacological and surgical treatments, the …

Glioblastoma (GBM) remains the most lethal and common primary brain tumor, even after
treatment with multiple therapies, such as surgical resection, chemotherapy, and radiation …

Recently, lipid metabolism reprogramming has been further evidenced in malignancies via
the observation of large amounts of lipid droplets (LDs) in human tumors, including in …

Circular RNAs (circRNAs) are a type of single-stranded RNA molecules forming a covalently
closed, continuous structure, lacking 5′-3′ polarity and polyadenylated tails. Recent …

Purpose The aim of this work is to review the published studies on radiation resistance
mechanisms and molecular markers involved in different tumors. The revision has been …

Oncolytic viruses (OVs) are emerging cancer immunotherapy. Despite notable successes in
the treatment of some tumors, OV therapy for central nervous system cancers has failed to …

Human acid ceramidase (AC) is a lysosomal cysteine amidase, which has received a great
deal of interest in recent years as a potential target for the development of new therapeutics …

Glioblastoma (GBM) is the most commonly diagnosed malignant brain tumor in adults. The
prognosis for patients with GBM remains poor and largely unchanged over the last 30 years …

High-grade gliomas (HGG) represent about 15% of all pediatric brain tumors, with a dismal
prognosis and survival rates ranging from 15 to 35%. Approximately 10–12% of pediatric …

Although over 100 species of Curcuma are reported, only Curcuma longa is extensively
studied. Curcuma raktakanda, a poorly studied species, is most commonly distributed in the …