Immune Responses to Bacillus Calmette–Guérin Vaccination: Why Do They Fail to Protect against Mycobacterium tuberculosis?
Mycobacterium tuberculosis (M. tb), the causative agent of tuberculosis (TB), is the current
leading cause of death due to a single infectious organism. Although curable, the broad …
leading cause of death due to a single infectious organism. Although curable, the broad …
Multi-stage subunit vaccines against Mycobacterium tuberculosis: an alternative to the BCG vaccine or a BCG-prime boost?
F Khademi, M Derakhshan… - Expert review of …, 2018 - Taylor & Francis
Introduction: More than two billion people are latently infected with Mycobacterium
tuberculosis. Most tuberculosis (TB)-subunit vaccines currently in various stages of clinical …
tuberculosis. Most tuberculosis (TB)-subunit vaccines currently in various stages of clinical …
Dendritic cell-based vaccine efficacy: aiming for hot spots
GA Pizzurro, MM Barrio - Frontiers in immunology, 2015 - frontiersin.org
Many approaches for cancer immunotherapy have targeted dendritic cells (DCs), directly or
indirectly, for the induction of antitumor immune responses. DC-based vaccines have been …
indirectly, for the induction of antitumor immune responses. DC-based vaccines have been …
Chitosan nanoparticles containing fusion protein (Hspx–PPE44–EsxV) and resiquimod adjuvant (HPERC) as a novel booster vaccine for Mycobacterium tuberculosis
This study attempted to explore the immunogenicity of chitosan nanoparticles containing
fusion protein (Hspx–PPE44–EsxV; HPE) and resiquimod adjuvant (HPERC) in BALB/c …
fusion protein (Hspx–PPE44–EsxV; HPE) and resiquimod adjuvant (HPERC) in BALB/c …
Comparative Genomics and Proteomic Analysis of Four Non-tuberculous Mycobacterium Species and Mycobacterium tuberculosis Complex: Occurrence of Shared …
N Gcebe, A Michel, NC Gey van Pittius… - Frontiers in …, 2016 - frontiersin.org
The Esx and PE/PPE families of proteins are among the most immunodominant
mycobacterial antigens and have thus been the focus of research to develop vaccines and …
mycobacterial antigens and have thus been the focus of research to develop vaccines and …
Enhancement of the effect of BCG vaccine against tuberculosis using DDA/TDB liposomes containing a fusion protein of HspX, PPE44, and EsxV
D Mansury, K Ghazvini, S Amel Jamehdar… - Artificial Cells …, 2019 - Taylor & Francis
Tuberculosis has been a major health problem worldwide for years; therefore, it is important
to develop and produce an effective vaccine against this disease. In this study, the …
to develop and produce an effective vaccine against this disease. In this study, the …
Role of ATP-small heat shock protein interaction in human diseases
Adenosine triphosphate (ATP) is an important fuel of life for humans and Mycobacterium
species. Its potential role in modulating cellular functions and implications in systemic …
species. Its potential role in modulating cellular functions and implications in systemic …
HspX protein as a candidate vaccine against Mycobacterium tuberculosis: an overview
Background Tuberculosis (TB) is a contagious infectious disease caused by Mycobacterium
tuberculosis (Mtb). This disease with two million deaths per year has the highest mortality …
tuberculosis (Mtb). This disease with two million deaths per year has the highest mortality …
Mycobacterium tuberculosis virulence protein ESAT-6 influences M1/M2 polarization and macrophage apoptosis to regulate tuberculosis progression
F Sun, J Li, L Cao, C Yan - Genes & Genomics, 2024 - Springer
Background Tuberculosis (TB) is an infectious disease caused by infection with
Mycobacterium tuberculosis (Mtb), and it remains one of the major threats to human health …
Mycobacterium tuberculosis (Mtb), and it remains one of the major threats to human health …
[HTML][HTML] Enhancing immunogenicity of novel multistage subunit vaccine of Mycobacterium tuberculosis using PLGA: DDA hybrid nanoparticles and MPLA …
Objective (s): A new strategy in recent studies is using effective tuberculosis (TB) subunit
vaccines combined with appropriate carriers and adjuvants which have shown promising …
vaccines combined with appropriate carriers and adjuvants which have shown promising …