Humans are spending an increasing amount of time in space, where exposure to conditions
of microgravity causes 1–2% bone loss per month in astronauts. Through data collected …

The regeneration of bone fractures, resulting from trauma, osteoporosis or tumors, is a major
problem in our super-aging society. Bone regeneration is one of the main topics of concern …

Disuse osteoporosis describes a state of bone loss due to local skeletal unloading or
systemic immobilization. This review will discuss advances in the field that have shed light …

Bone loss in space travelers is a major challenge for long-duration space exploration. To
quantify microgravity-induced bone loss in humans, we performed a meta-analysis of …

The field of human space travel is in the midst of a dramatic revolution. Upcoming missions
are looking to push the boundaries of space travel, with plans to travel for longer distances …

Abstract Space sojourns are challenging for life. The ability of the human body to adapt to
these extreme conditions has been noted since the beginning of human space travel …

Determining the extent of bone recovery after prolonged spaceflight is important for
understanding risks to astronaut long-term skeletal health. We examined bone strength …

Objectives Bone loss remains a primary health concern for astronauts, despite in-flight
exercise. We examined changes in bone microarchitecture, density and strength before and …

For centuries, regular exercise has been acknowledged as a potent stimulus to promote,
maintain, and restore healthy functioning of nearly every physiological system of the human …

Multiple transitions between gravity levels will occur during planetary exploration missions.
In reaction to these gravitational transitions, physiological adaptation will be initiated …