Neurons of the mammalian central nervous system fail to regenerate. Substantial progress
has been made toward identifying the cellular and molecular mechanisms that underlie …

The corticospinal tract (CST) plays a major role in cortical control of spinal cord activity. In
particular, it is the principal motor pathway for voluntary movements. Here, we discuss:(i) the …

Retinal ganglion cells (RGCs) convey the major output of information collected from the eye
to the brain. Thirty subtypes of RGCs have been identified to date. Here, we analyze 6225 …

How a sensory stimulus is processed and perceived depends on the surrounding sensory
scene. In the visual cortex, contextual signals can be conveyed by an extensive network of …

Vision is the sense humans rely on most to navigate the world, make decisions, and perform
complex tasks. Understanding how humans see thus represents one of the most …

Localized mRNA translation regulates synapse function and axon maintenance, but how
compartment-specific mRNA repertoires are regulated is largely unknown. We developed an …

The mature optic nerve cannot regenerate when injured, leaving victims of traumatic nerve
damage or diseases such as glaucoma with irreversible visual losses. Recent studies have …

Patterns of synaptic connections in the visual system are remarkably precise. These
connections dictate the receptive field properties of individual visual neurons and ultimately …

Predators use vision to hunt, and hunting success is one of evolution's main selection
pressures. However, how viewing strategies and visual systems are adapted to predation is …

Brain connections are organized into topographic maps that are precisely aligned both
within and across modalities. This alignment facilitates coherent integration of different …