The glymphatic system and waste clearance with brain aging: a review

H Benveniste, X Liu, S Koundal, S Sanggaard, H Lee… - Gerontology, 2019 - karger.com
The glymphatic system is a glial-dependent waste clearance pathway in the brain, in place
of lymphatic vessels, dedicated to drain away soluble waste proteins and metabolic …

Interleukin-6 in neuromyelitis optica spectrum disorder pathophysiology

K Fujihara, JL Bennett, J de Seze… - Neurology …, 2020 - AAN Enterprises
Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune disorder that
preferentially affects the spinal cord and optic nerve. Most patients with NMOSD experience …

A new look at cerebrospinal fluid circulation

T Brinker, E Stopa, J Morrison, P Klinge - Fluids and Barriers of the CNS, 2014 - Springer
According to the traditional understanding of cerebrospinal fluid (CSF) physiology, the
majority of CSF is produced by the choroid plexus, circulates through the ventricles, the …

Disorders of plasma sodium—causes, consequences, and correction

RH Sterns - New England Journal of Medicine, 2015 - Mass Medical Soc
Human cells dwell in salt water. Their well-being depends on the ability of the body to
regulate the salinity of extracellular fluids. By controlling water intake and excretion, the …

Astrocytes as guardians of neuronal excitability: mechanisms underlying epileptogenesis

QP Verhoog, L Holtman, E Aronica… - Frontiers in …, 2020 - frontiersin.org
Astrocytes are key homeostatic regulators in the central nervous system and play important
roles in physiology. After brain damage caused by eg, status epilepticus, traumatic brain …

The role of water homeostasis in muscle function and frailty: a review

I Lorenzo, M Serra-Prat, JC Yébenes - Nutrients, 2019 - mdpi.com
Water, the main component of the body, is distributed in the extracellular and intracellular
compartments. Water exchange between these compartments is mainly governed by …

The water transport system in astrocytes–Aquaporins

Z Zhou, J Zhan, Q Cai, F Xu, R Chai, K Lam, Z Luan… - Cells, 2022 - mdpi.com
Highlights (AQPs) are transmembrane proteins responsible for fast water movement across
cell membranes, including those of astrocytes. The expression and subcellular localization …

Regulation of blood flow and volume exchange across the microcirculation

M Jacob, D Chappell, BF Becker - Critical care, 2016 - Springer
Oxygen delivery to cells is the basic prerequisite of life. Within the human body, an
ingenious oxygen delivery system, comprising steps of convection and diffusion from the …

Toward understanding the selective anticancer capacity of cold atmospheric plasma—A model based on aquaporins

D Yan, A Talbot, N Nourmohammadi, JH Sherman… - …, 2015 - pubs.aip.org
Selectively treating tumor cells is the ongoing challenge of modern cancer therapy.
Recently, cold atmospheric plasma (CAP), a near room-temperature ionized gas, has been …

Human aquaporins: functional diversity and potential roles in infectious and non-infectious diseases

AK Azad, T Raihan, J Ahmed, A Hakim, TH Emon… - Frontiers in …, 2021 - frontiersin.org
Aquaporins (AQPs) are integral membrane proteins and found in all living organisms from
bacteria to human. AQPs mainly involved in the transmembrane diffusion of water as well as …