Cytochrome P450 enzymes (P450s) are broadly distributed among living organisms and
play crucial roles in natural product biosynthesis, degradation of xenobiotics, steroid …

Since its introduction in 1982, biopharmaceutical drugs have revolutionized the treatment of
a broad spectrum of diseases and are increasingly used in nearly all branches of medicine …

Cytochromes P450 (CYPs) belong to the superfamily of heme b containing
monooxygenases with currently more than 21,000 members. These enzymes accept a vast …

Cytochromes P450 (P450 or CYP) are heme-containing enzymes that catalyze the
introduction of one atom of molecular oxygen into nonactivated C–H bonds, often in a regio …

Competitive sustainable production in industry demands new and better biocatalysts,
optimized bioprocesses and cost-effective product recovery. Our review sheds light on the …

Abstract Cytochrome P450 (CYP) monooxygenases, the nature's most versatile biological
catalysts have unique ability to catalyse regio-, chemo-, and stereospecific oxidation of a …

Biomolecular engineering can be used to purposefully manipulate biomolecules, such as
peptides, proteins, nucleic acids and lipids, within the framework of the relations among their …

Cytochrome P450s are heme-thiolate enzymes that have been broadly applied in
pharmaceutical and biosynthesis because of their efficient oxidation at inert carbons …

P450s are heme thiolate enzymes that catalyze the regio-and stereoselective
functionalization of unactivated C–H bonds using molecular dioxygen and two electrons …

Cytochrome P450 (CYP) enzymes play crucial roles during the evolution and diversification
of ancestral monocellular eukaryotes into multicellular eukaryotic organisms due to their …