[HTML][HTML] Targeting endothelial cells with golden spice curcumin: A promising therapy for cardiometabolic multimorbidity

F Tang, D Liu, L Zhang, LY Xu, JN Zhang… - Pharmacological …, 2023 - Elsevier
Cardiometabolic multimorbidity (CMM) is an increasingly significant global public health
concern. It encompasses the coexistence of multiple cardiometabolic diseases, including …

Curcumin and endothelial function: evidence and mechanisms of protective effects

M S. Karimian, M Pirro, T P. Johnston… - Current …, 2017 - benthamdirect.com
Background: The endothelium is a large paracrine organ regulating cell growth, vascular
tone and thrombogenicity as well as platelet and leukocyte interactions. Endothelial function …

Microparticles-mediated vascular inflammation and its amelioration by antioxidant activity of baicalin

KR Paudel, DW Kim - Antioxidants, 2020 - mdpi.com
Microparticles (MPs) are extracellular vesicles (0.1–1.0 μm in size), released in response to
cell activation or apoptosis. Endothelial microparticles (EC-MP), vascular smooth muscle cell …

Enhanced effects of curcumin encapsulated in polycaprolactone-grafted oligocarrageenan nanomicelles, a novel nanoparticle drug delivery system

L Youssouf, A Bhaw-Luximon, N Diotel, A Catan… - Carbohydrate …, 2019 - Elsevier
One of the most effective strategies to enhance the bioavailability and the therapeutic effect
of hydrophobic drugs is the use of nanocarriers. We have used κ-carrageenan extracted …

Ultrasensitive cytosensor based on self-enhanced electrochemiluminescent ruthenium-silica composite nanoparticles for efficient drug screening with cell apoptosis …

W Liang, Y Zhuo, C Xiong, Y Zheng, Y Chai… - Analytical …, 2015 - ACS Publications
The self-enhanced electrochemiluminescence (ECL) with high sensitivity could be an
effective method for anticancer drug screening with cell apoptosis monitoring. Here we …

The effects of curcumin supplementation on metabolic biomarkers and body mass index in patients with nonalcoholic fatty liver disease: A systematic review and meta …

L Khalili, S Nammi - Current pharmaceutical design, 2022 - ingentaconnect.com
Background and Aims: Curcumin is one of the most commonly used indigenous molecules
endowed with various shielding functionalities that protect the liver. In the present research …

Role of curcumin in ameliorating hypertension and associated conditions: a mechanistic insight

P Joshi, S Joshi, DK Semwal, K Verma… - Molecular and Cellular …, 2022 - Springer
Curcumin, belongs to the curcuminoid family, is a natural phenolic compound, presenting
low bioavailability and pleiotropic activity. Since ancient times, curcumin has been in use as …

Protective effects of curcumin on endothelium: An updated review

M Alidadi, L Liberale, F Montecucco, M Majeed… - Studies on Biomarkers …, 2021 - Springer
Endothelial dysfunction is the common early stage of most cardiovascular afflictions. The
endothelium is considered the main mediator of vascular homeostasis via its vasodilator …

Extracellular vesicles as mediators of immunopathology in infectious diseases

E Hosseini‐Beheshti, GER Grau - Immunology and Cell Biology, 2018 - Wiley Online Library
In the last decades, extracellular vesicles have emerged as important elements in cell–cell
communication and as key players in disease pathogenesis via transmission of their cargo …

Protective effects of curcumin on corneal endothelial cell PANoptosis and monocyte adhesion induced by tumor necrosis factor-alpha and interferon-gamma in rats

R Guo, Y Yu, C Xu, M Ma, C Hou, X Dong, J Wu… - Experimental Eye …, 2024 - Elsevier
Decrease of human corneal endothelial cell (CEC) density leads to corneal edema,
progressive corneal opacity, and reduced visual acuity. A reduction in CEC density may be …