The ice crystallization and melting in systems where the equilibrium state is difficult to reach
is one of the growing areas in pharmaceutical freeze-drying research. The quality of the final …

Overuse injuries or acute trauma in joints often lead to painful tendinopathy, and
pharmacological treatment effects are limited. The site of the disease is hard to reach with …

Solid-state NMR methods incorporating dynamics-based spectral editing have a remarkable
versatility for resolving and separately characterizing co-existing solid and liquid phases or …

Preclinical studies for wound healing disorders are an essential step in translating
discoveries into therapies. Also, they are an integral component of initial safety screening …

The term “animal model” refers to a non-human species employed in biomedical research
due to its capacity to replicate certain biological processes or diseases found in humans …

Equilibrium water sorption in stratum corneum (SC) is considered by treating it as a
biocomposite with two main phases, namely, corneocytes and lipids. To validate the rule of …

Arnica tincture is a traditional herbal medicine used to treat blunt injuries, eg, bruises and
squeezes. In addition, a potential new use in the treatment of cutaneous leishmaniasis is …

Skin abrasion wounds, especially those infected with methicillin-resistant Staphylococcus
aureus (MRSA), pose a risk of developing into severe lesions. MRSA is resistant to typical …

Arnica tincture is a traditional herbal medicine used to treat blunt injuries, eg, bruises and
squeezes. In addition, a potential new use in the treatment of cutaneous leishmaniasis is …

This thesis presents a significant advance in selection of drug candidates for transdermal
drug delivery. The methodology uses molecular dynamics simulations to understand the …