The association between mutations of key driver genes and colorectal cancer (CRC)
metastasis has been investigated by many studies. However, the results of these studies …

Background: Several studies have suggested that microsatellite instability (MSI) resulting
from defective DNA mismatch repair confers a better prognosis in colorectal cancer (CRC) …

Purpose To update the recommendations for the use of tumor marker tests in the prevention,
screening, treatment, and surveillance of gastrointestinal cancers. Methods For the 2006 …

Colon cancer is believed to arise from two types of precursor polyps via two distinct
pathways: conventional adenomas by the conventional adenoma-to-carcinoma sequence …

Understanding of the mechanism of colorectal carcinogenesis has been gaining momentum
for some years on account of its high incidence and impact on the lives of individuals …

Molecular Biology of Cancer has been extensively revised and covers heredity cancer,
microarray technology and increased study of childhood cancers. It continues to provide a …

PURPOSE: Colorectal cancer is one of the most common forms of cancer in developed
nations and the incidence of this disease is increasing. There is a need to further stratify …

Background p53 (encoded by TP53) is involved in DNA damage repair, cell cycle regulation,
apoptosis, aging and cellular senescence. TP53 is mutated in around 50% of human …

Background In terms of genetics, colorectal cancer is one of the best understood of all
malignant diseases. Genetic influences on prognosis may have far-reaching implications …

Purpose: In colorectal cancer, the negative effect of aneuploidy has been a controversy for
more than 20 years. Studies to determine a survival-deoxyribonucleic acid content …