Since the discovery of MSP (macrophage-stimulating protein; also known as MST1 and
hepatocyte growth factor-like (HGFL)) as the ligand for the receptor tyrosine kinase RON …

The Ron receptor is a member of the Met family of cell surface receptor tyrosine kinases and
is primarily expressed on epithelial cells and macrophages. The biological response of Ron …

The HGF/MET signaling pathway regulates a wide variety of normal cellular functions that
can be subverted to support neoplasia, including cell proliferation, survival, apoptosis …

The RON receptor tyrosine kinase is a member of the MET proto-oncogene family that has
been implicated in regulating motile-invasive phenotypes in certain types of epithelial …

Colorectal cancer is the third most common malignancy in men and the second most
common cancer in women. Despite the success of screening programs and the …

The product of the RON (recepteur d'origine nantais) gene belongs to the MET proto-
oncogene family, a distinct subfamily of receptor tyrosine kinases. The ligand of RON was …

RON is a member of the c-MET receptor tyrosine kinase family. Like c-MET, RON is
expressed by a variety of epithelial-derived tumors and cancer cell lines and it is thought to …

Pancreatic cancer is an aggressive disease characterized by rapid growth and early
metastasis. The recepteur d'origine nantais (RON) receptor tyrosine kinase is overexpressed …

Aberrant expression of the RON receptor tyrosine kinase has been implicated in the
pathogenesis of epithelial tumours. The aim of this study was to determine RON expression …

Tyrosine kinase receptors mediate many critical cellular functions that contribute to tumor
progression and metastasis and thus are potential targets for molecular-based cancer …