A (GCC) repeat in SBF1 reveals a novel biological phenomenon in human and links to late onset neurocognitive disorder
S Khamse, S Alizadeh, SH Bernhart, H Afshar… - Scientific Reports, 2022 - nature.com
The human SBF1 (SET binding factor 1) gene, alternatively known as MTMR5, is
predominantly expressed in the brain, and its epigenetic dysregulation is linked to late-onset …
predominantly expressed in the brain, and its epigenetic dysregulation is linked to late-onset …
[HTML][HTML] ДНК маркеры и «микросателлитный код»(обзор)
ВИ Глазко, ГЮ Косовский, ТТ Глазко… - …, 2023 - agrobiology.ru
Одной из центральных проблем в современном животноводстве остается поиск
генетических маркеров, которые упростили бы отбор и подбор животных для …
генетических маркеров, которые упростили бы отбор и подбор животных для …
CRISPR/Cas9-mediated deletion of a GA-repeat in human GPM6B leads to disruption of neural cell differentiation from NT2 cells
The human neuron-specific gene, GPM6B (Glycoprotein membrane 6B), is considered a key
gene in neural cell functionality. This gene contains an exceptionally long and strictly …
gene in neural cell functionality. This gene contains an exceptionally long and strictly …
Novel islands of GGC and GCC repeats coincide with human evolution
N Tajeddin, M Arabfard, S Alizadeh, M Salesi… - Gene, 2024 - Elsevier
Background Because of high mutation rate, overrepresentation in genic regions, and link
with various neurological, neurodegenerative, and movement disorders, GGC and GCC …
with various neurological, neurodegenerative, and movement disorders, GGC and GCC …
Dyads of GGC and GCC form hotspot colonies that coincide with the evolution of human and other great apes
M Arabfard, N Tajeddin, S Alizadeh, M Salesi… - BMC Genomic …, 2024 - Springer
Background GGC and GCC short tandem repeats (STRs) are of various evolutionary,
biological, and pathological implications. However, the fundamental two-repeats (dyads) of …
biological, and pathological implications. However, the fundamental two-repeats (dyads) of …
[PDF][PDF] DNA markers and microsatellite code
VI Glazko, GY Kosovsky, TT Glazko… - Sel' …, 2023 - agrobiology.ru
The search for genetic markers that simplify the selection of animals for crosses, increasing
the likelihood of offspring obtaining with the desired manifestation of economically valuable …
the likelihood of offspring obtaining with the desired manifestation of economically valuable …
A primate-specific (GCC) repeat in SMAD9 undergoes natural selection in humans and harbors unambiguous genotypes in late-onset neurocognitive disorder.
S Alizadeh, S Khamse, SH Bernhart, M Vahedi… - 2022 - researchsquare.com
Across numerous primate species and tissues, SMAD9 (SMAD Family Member 9) reaches
the highest level of expression in the human brain. This gene contains a (GCC) short …
the highest level of expression in the human brain. This gene contains a (GCC) short …
The human SMAD9 (GCC) repeat links to natural selection and late-onset neurocognitive disorders
S Alizadeh, S Khamse, S Vafadar, SH Bernhart… - Neurological …, 2024 - Springer
Introduction Whereas (GCC)-repeats are overrepresented in genic regions, and mutation
hotspots, they are largely unexplored with regard to their link with natural selection. Across …
hotspots, they are largely unexplored with regard to their link with natural selection. Across …
CG-rich trinucleotide two-repeats may be the long-sought recombination hotspot loci shared across primates and mouse
CG-rich trinucleotide short tandem repeats (STRs) are linked with human cognition and
various neurodevelopmental, neurological, and movement disorders. However, the …
various neurodevelopmental, neurological, and movement disorders. However, the …
Deletion of a GA-repeat in human GPM6B disrupts differentiation of NT2 cells to neural cells
Across multiple primates and tissues, GPM6B (Glycoprotein membrane 6B) reaches
maximum levels of expression in the human brain. This gene contains a strictly …
maximum levels of expression in the human brain. This gene contains a strictly …